Nature Search

Core Phase Transition of Radiation-Modified Polysilane Micelles as Revealed from Their Thermochromism

Hidenori Tanaka
Nobuhiro Sato
Toshiji Kanaya
Research12 Jun 2007
Polymer Journal

Volume: 39, P: 874-877
New insight into the dynamical system of αB-crystallin oligomers

Rintaro Inoue
Takumi Takata
Masaaki Sugiyama
ResearchOpen Access06 Jul 2016
Scientific Reports

Volume: 6, P: 1-7
C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers

Nuclear import receptors (NIRs) regulate self-association of RNA-binding proteins as phase modifiers, while C9orf72-derived arginine-rich polydipeptides lead to aberrant phase transitions. Here the authors show in molecular basis how arginine-rich poly-dipeptides impede the ability of NIRs, particularly Kapβ2.

Hitoki Nanaura
Honoka Kawamukai
Eiichiro Mori
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-12
Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

Rintaro Yoshida
Kaname Miyashita
Yoshihiko Maehara
Research15 Dec 2010
European Journal of Human Genetics

Volume: 19, P: 320-325
Structural characterization of the circadian clock protein complex composed of KaiB and KaiC by inverse contrast-matching small-angle neutron scattering

Masaaki Sugiyama
Hirokazu Yagi
Koichi Kato
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-7
Dynamics of proteins with different molecular structures under solution condition

Rintaro Inoue
Takashi Oda
Masaaki Sugiyama
ResearchOpen Access10 Dec 2020
Scientific Reports

Volume: 10, P: 1-10
Early aggregation preceding the nucleation of insulin amyloid fibrils as monitored by small angle X-ray scattering

Eri Chatani
Rintaro Inoue
Toshiji Kanaya
ResearchOpen Access27 Oct 2015
Scientific Reports

Volume: 5, P: 1-14
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

The FANTOM4 study identified transcriptional start sites active during proliferation arrest and differentiation of the human monocytic cell line THP-1. Systematic knockdown of 52 transcription factors provide support for their model in which a complex transcriptional network regulates the differentiation process.

Harukazu Suzuki
Alistair R R Forrest
Yoshihide Hayashizaki
Research19 Apr 2009
Nature Genetics

Volume: 41, P: 553-562
Elucidation of the mechanism of subunit exchange in αB crystallin oligomers

Rintaro Inoue
Yusuke Sakamaki
Masaaki Sugiyama
ResearchOpen Access28 Jan 2021
Scientific Reports

Volume: 11, P: 1-9
Newly developed Laboratory-based Size exclusion chromatography Small-angle x-ray scattering System (La-SSS)

Rintaro Inoue
Tatsuo Nakagawa
Masaaki Sugiyama
ResearchOpen Access30 Aug 2019
Scientific Reports

Volume: 9, P: 1-12
Structure analyses of polybutadiene rubber crosslinked with unsaturated carboxylate using contrast variation small-angle neutron scattering

We studied the structure of polybutadiene rubber (BR) crosslinked with zinc diacrylate (ZDA) to elucidate the structure of the high crosslink density BR (HC-BR) using a contrast variation small-angle neutron scattering (CV-SANS) method. The careful analysis revealed the existence of a HC-BR layer around the ZDA aggregates. This is the first time quantitative structural analysis of the HC-BR layer in this rubber material has been performed. In addition, the network structure of the HC-BR layer in the rubber matrix is responsible for the high mechanical modulus of the rubber.

Ryo Mashita
Hiroyuki Kishimoto
Toshiji Kanaya
Research28 Oct 2015
Polymer Journal

Volume: 48, P: 239-245
Structural analysis of poly(ethylene terephthalate) during uniaxial drawing above the glass transition temperature

We performed small-angle and wide-angle X-ray scattering (SAXS/WAXS) measurements on poly(ethylene terephthalate) (PET) uniaxially drawn from amorphous state above the glass transition temperature. The measurements were done at a new beamline (BL) BL03XU (Frontier Softmaterial Bamline) in the synchrotron radiation X-ray facility, SPring-8, which is dedicated to development of advanced soft materials and belongs to the Advanced Softmaterial BL Consortium. We performed a calculation to reproduce the observed 2D SAXS patterns. Based on the results of the calculation we discussed the distribution of lamellar stacking direction and the relation between the lamellar length and the stacking direction.

Kazuyuki Okada
Takuji Higashioji
Toshiji Kanaya
Research21 Nov 2012
Polymer Journal

Volume: 45, P: 50-56
Small-angle X-ray and neutron scattering analyses of highly crosslinked rubber with unsaturated carboxylic acid

We studied the structure of polybutadiene rubber (BR) crosslinked with zinc diacrylate (ZDA) by complementary use of small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS) to confirm the high crosslink density region in the matrix rubber. This is the first finding of the high crosslink density segments in BR (HC-BR) crosslinked by ZDA. Tensile measurements revealed that the size and the number density of the HC-BR and ZDA aggregates are related to the mechanical property of the rubber materials.

Ryo Mashita
Hiroyuki Kishimoto
Toshiji Kanaya
Research21 Nov 2012
Polymer Journal

Volume: 45, P: 57-63
Role of molecular weight in shish-kebab formation during drawing by small-angle neutron and X-ray scattering

Small-angle neutron and X-ray scattering measurements were conducted on blends of deuterated polyethylene and hydrogenateted polyethylene with various molecular weights drawn just below the melting temperature at three drawing rates to study role of molecular weigh in shish-kebab formation. It was found that low molecular weight component was mainly included in shish for the present experimental condition. The result contradicts our previous result, showing that there are various shish-kebab formation mechanisms that are not known so far.

Toshiji Kanaya
Momoko Murakami
Tae-Hwan Kim
Research11 Oct 2017
Polymer Journal

Volume: 49, P: 831-837
Extracting time series matching a small-angle X-ray scattering profile from trajectories of molecular dynamics simulations

Masahiro Shimizu
Aya Okuda
Masaaki Sugiyama
ResearchOpen Access15 Jun 2022
Scientific Reports

Volume: 12, P: 1-13
Overall structure of fully assembled cyanobacterial KaiABC circadian clock complex by an integrated experimental-computational approach

The revealed full KaiA₁₂B₆C₆ complex is assembled including the dynamic and asynchronous KaiA N-terminal domains that have been missing in cryo-EM structures.

Yasuhiro Yunoki
Atsushi Matsumoto
Masaaki Sugiyama
ResearchOpen Access10 Mar 2022
Communications Biology

Volume: 5, P: 1-12
Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome

Hirano et al. show that the H2A.B-H2B histone dimer incorporated within the nucleosome exchanges with the canonical H2A-H2B dimer without assistance from histone chaperones or nucleosome remodelers. This study provides insights into how the H2A.B nucleosome exchanges its histones.

Rina Hirano
Yasuhiro Arimura
Hitoshi Kurumizaka
ResearchOpen Access12 Feb 2021
Communications Biology

Volume: 4, P: 1-11
Solution structure of multi-domain protein ER-60 studied by aggregation-free SAXS and coarse-grained-MD simulation

Aya Okuda
Masahiro Shimizu
Masaaki Sugiyama
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-13
Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation

Maho Yagi-Utsumi
Arunima Sikdar
Koichi Kato
ResearchOpen Access30 Jan 2020
Scientific Reports

Volume: 10, P: 1-10
Integral approach to biomacromolecular structure by analytical-ultracentrifugation and small-angle scattering

Ken Morishima et al. integrate small-angle scattering (SAS) with analytical-ultracentrifugation (AUC) to analyze the scattering intensity of biomacromolecules in solution. Their new approach allows to correct for the aggregation effect and can be applied to multi-component systems.

Ken Morishima
Aya Okuda
Masaaki Sugiyama
ResearchOpen Access08 Jun 2020
Communications Biology

Volume: 3, P: 1-7
A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

Junichi Kushioka
Takashi Kaito
Takeshi Imamura
ResearchOpen Access23 Nov 2020
Bone Research

Volume: 8, P: 1-10
Maternal impulse control disability and developmental disorder traits are risk factors for child maltreatment

Yoshiyuki Tachibana
Kenji Takehara
Takahiko Kubo
ResearchOpen Access14 Nov 2017
Scientific Reports

Volume: 7, P: 1-12
Autologous cord blood cell therapy for neonatal hypoxic-ischaemic encephalopathy: a pilot study for feasibility and safety

Masahiro Tsuji
Mariko Sawada
Haruo Shintaku
ResearchOpen Access12 Mar 2020
Scientific Reports

Volume: 10, P: 1-10
In situ small-angle X-ray and neutron scattering measurements on a blend of deuterated and hydrogenated polyethylenes during uniaxial drawing

In situ small-angle X-ray and neutron scattering (SAXS and SANS) measurements were conducted on an isotropic blend of deuterated polyethylene (97 wt%) and hydrogenated polyethylene (3 wt%) during uniaxial drawing at 125 °C to clarify the formation mechanism of shish-kebab from isotropic film. Figure shows that 2D SANS and SAXS patterns in the various drawing ratio, R_D, conditions. The drawing direction is longitudinal. In R_D=8, the streak-like scattering in the normal direction of drawing became stronger only in the SANS, showing that more hydrogenated polyethylene chains were merged into the shish.

Go Matsuba
Chie Ito
Toshiji Kanaya
Research01 Aug 2012
Polymer Journal

Volume: 45, P: 293-299

Search

Core Phase Transition of Radiation-Modified Polysilane Micelles as Revealed from Their Thermochromism

New insight into the dynamical system of αB-crystallin oligomers

C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers

Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

Structural characterization of the circadian clock protein complex composed of KaiB and KaiC by inverse contrast-matching small-angle neutron scattering

Dynamics of proteins with different molecular structures under solution condition

Early aggregation preceding the nucleation of insulin amyloid fibrils as monitored by small angle X-ray scattering

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

Elucidation of the mechanism of subunit exchange in αB crystallin oligomers

Newly developed Laboratory-based Size exclusion chromatography Small-angle x-ray scattering System (La-SSS)

Structure analyses of polybutadiene rubber crosslinked with unsaturated carboxylate using contrast variation small-angle neutron scattering

Structural analysis of poly(ethylene terephthalate) during uniaxial drawing above the glass transition temperature

Small-angle X-ray and neutron scattering analyses of highly crosslinked rubber with unsaturated carboxylic acid

Role of molecular weight in shish-kebab formation during drawing by small-angle neutron and X-ray scattering

Extracting time series matching a small-angle X-ray scattering profile from trajectories of molecular dynamics simulations

Overall structure of fully assembled cyanobacterial KaiABC circadian clock complex by an integrated experimental-computational approach

Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome

Solution structure of multi-domain protein ER-60 studied by aggregation-free SAXS and coarse-grained-MD simulation

Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation

Integral approach to biomacromolecular structure by analytical-ultracentrifugation and small-angle scattering

A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

Maternal impulse control disability and developmental disorder traits are risk factors for child maltreatment

Autologous cord blood cell therapy for neonatal hypoxic-ischaemic encephalopathy: a pilot study for feasibility and safety

In situ small-angle X-ray and neutron scattering measurements on a blend of deuterated and hydrogenated polyethylenes during uniaxial drawing

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