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Showing 1–2 of 2 results
Advanced filters: Author: Risako Gen Clear advanced filters

  • The HKU25 clade MERS-related coronaviruses with broad distribution are shown to use ACE2 as a functional receptor, revealing unexpected receptor plasticity and offering new insights into coronavirus evolution, host range and potential zoonotic risk.

    • Chen Liu
    • Young-Jun Park
    • Huan Yan
    ResearchOpen Access
    Nature Microbiology
    Volume: 10, P: 2860-2874

  • The precise regulatory mechanisms controlling ciliary Hedgehog signaling remain incomplete. Here, the authors use ciliary proteomics to reveal that Numb facilitates the endocytosis of the receptor Ptch1 from the ciliary pocket, thereby enabling activation of Hedgehog signaling.

    • Xiaoliang Liu
    • Patricia T. Yam
    • Xuecai Ge
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20