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Showing 1–2 of 2 results
Advanced filters: Author: Rishith Ravindran Clear advanced filters

  • In this Review, Ravindran and Gustafsson describe the mechanisms involved in regulating mitochondrial quality control in cardiomyocytes, discuss how these pathways are altered in cardiovascular disease and ageing, and highlight the therapeutic potential of targeting mitochondrial quality control pathways in cardiovascular disease.

    • Rishith Ravindran
    • Åsa B. Gustafsson
    Reviews
    Nature Reviews Cardiology
    Volume: 22, P: 798-813

  • Mitochondrial quality control is critical for cellular homeostasis and survival. Here, the authors identify that defective mitochondria can be eliminated via secretion in large extracellular vesicles when internal lysosomal degradation is compromised.

    • Wenjing Liang
    • Shakti Sagar
    • Åsa B. Gustafsson
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18