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Showing 1–2 of 2 results
Advanced filters: Author: Ritu Sarpal Clear advanced filters

  • Cell-cell adhesion mediated by catenin-cadherin complexes plays a critical role in translating the mechanical forces into physiological responses. Here the authors define a mechanism of force-dependent cadherin-actin linkage dynamically regulated through the actin-binding domain of α-catenin.

    • Noboru Ishiyama
    • Ritu Sarpal
    • Mitsuhiko Ikura
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-17

  • Tepass and colleagues use a series of mutant α-catenin forms to study the role of this protein in Drosophila in vivo. Their data support a model in which monomeric α-catenin links the cadherin–β-catenin complex at adherens junction to the actin cytoskeleton.

    • Ridhdhi Desai
    • Ritu Sarpal
    • Ulrich Tepass
    Research
    Nature Cell Biology
    Volume: 15, P: 261-273