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Showing 1–2 of 2 results
Advanced filters: Author: Rober Abdo Clear advanced filters

  • Brain metastases (BrMs) in non-small cell lung cancer (NSCLC) are associated with dismal outcomes, and are possibly sustained by the brain microenvironment. Here, the authors analyse NSCLC BrMs using Digital Spatial Profiling and reveal fibrosis, immune suppression, and cell reprogramming in the BrM microenvironment.

    • Qi Zhang
    • Rober Abdo
    • Shawn Shun-Cheng Li
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-19

  • Kaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-mesenchymal transition and reprogrammed cytoskeletal signalling in recurrent tumours.

    • Tomonori Kaneko
    • Peter Y. F. Zeng
    • Shawn Shun-Cheng Li
    ResearchOpen Access
    Communications Medicine
    Volume: 2, P: 1-15