In this Technical Report, Kleinlogel and colleagues created and characterized a new channelrhodopsin-2 mutant with an enhanced permeability to calcium. Dubbed CatCh (calcium translocating channelrhodopsin), this new variant's enhanced calcium permeability mediates an accelerated response time and voltage response that is ~70-fold more light sensitive than that of wild-type channelrhodopsin-2.
- Sonja Kleinlogel
- Katrin Feldbauer
- Ernst Bamberg
