Nature Search

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

Theodore Fotsis
Youming Zhang
Lothar Schweigerer
Research17 Mar 1994
Nature

Volume: 368, P: 237-239
Microhaplotype deep sequencing assays to capture Plasmodium vivax infection lineages

Dormant liver stages of Plasmodium vivax complicate malaria elimination efforts by causing relapses that obscure the efficacy of antimalarial treatments. Here, the authors develop a high-throughput amplicon sequencing assay to reconstruct P. vivax lineages, demonstrating its capacity for geospatial infection tracking, and distinguishing recurrent malaria caused by new infections versus untreated dormant liver stages.

Mariana Kleinecke
Edwin Sutanto
Sarah Auburn
ResearchOpen Access05 Aug 2025
Nature Communications

Volume: 16, P: 1-14
The dynamic regenerative scaffold stenting and shielding hernia system for dissection-free, atraumatic hernioplasty. Results of an experimental animal study

Giuseppe Amato
Giorgio Romano
Antonino Agrusa
ResearchOpen Access31 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Assessment of an unsupervised denoising approach based on Noise2Void in digital mammography

Francesca Angelone
Alessandra Franco
Francesco Amato
ResearchOpen Access13 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

Here, a cross of Plasmodium vivax malaria parasites links a chloroquine resistance (CQR) phenotype to a 76 kb region of chromosome 1 and greater expression of pvcrt, an ortholog of the Plasmodium falciparum CQR transporter gene.

Juliana M. Sá
Sarah R. Kaslow
Thomas E. Wellems
ResearchOpen Access20 Sept 2019
Nature Communications

Volume: 10, P: 1-10
Unstable minisatellite expansion causing recessively inherited myoclonus epilepsy, EPM1

Kimmo Virtaneva
Elena D'Amato
Anna-Elina Lehesjoki
Research01 Apr 1997
Nature Genetics

Volume: 15, P: 393-396
SEX STEROIDS INFLUENCE ON URIC ACID BINDING TO HUMAN PLASMA PROTEINS: 136

Gabriella Morozzi
Maria S D'Amato
Roberto Marcolongo
Research01 Jul 1985
Pediatric Research

Volume: 19, P: 766
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Genetic and testing data from England show that the SARS-CoV-2 variant of concern B.1.1.7 has a transmission advantage over other lineages.

Erik Volz
Swapnil Mishra
Neil M. Ferguson
Research25 Mar 2021
Nature

Volume: 593, P: 266-269
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages

CRISPR-based gene drives have the potential to spread within populations and are considered as promising vector control tools. Here the authors show an anti-drive mosquito strain that prevents the spread and collapse of a population suppression gene drive in laboratory Anopheles mosquito large cage trials in complex ecological and behavioral conditions.

Rocco D’Amato
Chrysanthi Taxiarchi
Ruth Müller
ResearchOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1-12
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Lineage-informative microhaplotypes for recurrence classification and spatio-temporal surveillance of Plasmodium vivax malaria parasites

This work describes an informatic framework to identify multi-allelic markers in the genome of the malaria-causing Plasmodium vivax parasite that can inform on familial relatedness between infections. Spatial and temporal transmission patterns are demonstrated with an example marker set.

Sasha V. Siegel
Hidayat Trimarsanto
Sarah Auburn
ResearchOpen Access08 Aug 2024
Nature Communications

Volume: 15, P: 1-16
Genetic architecture of artemisinin-resistant Plasmodium falciparum

Dominic Kwiatkowski and colleagues report a large multicenter genome-wide association study of Plasmodium falciparum resistance to artemisinin. They identify markers of a genetic background on which kelch13 mutations conferring artemisinin resistance are likely to emerge.

Olivo Miotto
Roberto Amato
Dominic P Kwiatkowski
Research19 Jan 2015
Nature Genetics

Volume: 47, P: 226-234
Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1

Chloroquine resistance in Plasmodium falciparum is characterized using population genomics, genetic crosses and gene editing.

Alfred Amambua-Ngwa
Katrina A. Button-Simons
Timothy J. C. Anderson
ResearchOpen Access11 May 2023
Nature Microbiology

Volume: 8, P: 1213-1226
A lament for Italy's brain drain

Roberto Battiston
Books & Arts07 Feb 2002
Nature

Volume: 415, P: 582-583
Malaria protection due to sickle haemoglobin depends on parasite genotype

A strong association has been found between three regions of the Plasmodium falciparum genome and sickle haemoglobin in children with severe malaria, suggesting parasites have adapted to overcome natural host immunity.

Gavin Band
Ellen M. Leffler
Dominic P. Kwiatkowski
ResearchOpen Access09 Dec 2021
Nature

Volume: 602, P: 106-111
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

The Omicron variant evades vaccine-induced neutralization but also fails to form syncytia, shows reduced replication in human lung cells and preferentially uses a TMPRSS2-independent cell entry pathway, which may contribute to enhanced replication in cells of the upper airway. Altered fusion and cell entry characteristics are linked to distinct regions of the Omicron spike protein.

Brian J. Willett
Joe Grove
Emma C. Thomson
ResearchOpen Access07 Jul 2022
Nature Microbiology

Volume: 7, P: 1161-1179
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

Dinesh Aggarwal
Andrew J. Page
Ewan M. Harrison
ResearchOpen Access23 Feb 2022
Nature Communications

Volume: 13, P: 1-13
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

Dinesh Aggarwal
Ben Warne
Ian G. Goodfellow
ResearchOpen Access08 Feb 2022
Nature Communications

Volume: 13, P: 1-16
Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics

Plasmodium vivax incidence in Malaysia has declined markedly over the last decade, despite evidence of chloroquine resistance. Here, Auburn et al. compare population structure of P. vivax in Malaysia to regions with intermediate and high transmission and identify genetic regions under putative selection.

Sarah Auburn
Ernest D. Benavente
Ric N. Price
ResearchOpen Access03 Jul 2018
Nature Communications

Volume: 9, P: 1-12
Genomic analysis of local variation and recent evolution in Plasmodium vivax

Dominic Kwiatkowski and colleagues report a population genomic analysis of 228 clinical samples of Plasmodium vivax from 13 countries, with an emphasis on Southeast Asia. They analyze patterns of genetic structure within individual infections and find evidence for regional adaptation at the population level.

Richard D Pearson
Roberto Amato
Dominic P Kwiatkowski
Research27 Jun 2016
Nature Genetics

Volume: 48, P: 959-964
Evaluation of predictive factors for i-CLARAS (intraoperative complications in laparoscopic renal and adrenal surgery): a multicentre international retrospective cohort study

Angelo Territo
Giuseppe Di Buono
Francesco Vitale
ResearchOpen Access16 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Juggling resistance mutations

This month’s Genome Watch discusses how a better understanding of the genetic mechanisms of antimalarial drug resistance can maximize the utility of genomic surveillance programs in informing the most effective drug policy.

Gavin G. Rutledge
Roberto Amato
News27 Apr 2018
Nature Reviews Microbiology

Volume: 16, P: 332
SIGNIFICANCE deep learning based platform to fight illicit trafficking of Cultural Heritage goods

Eva Savina Malinverni
Dante Abate
Primo Zingaretti
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-12
Deep hierarchical subtyping of multi-organ systemic sclerosis trajectories - a EUSTAR study

Cécile Trottet
Manuel Schürch
Fatma Alibaz-Oner
ResearchOpen Access01 Sept 2025
npj Digital Medicine

Volume: 8, P: 1-12
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes

Federica Di Gennaro
Cinzia D’Amato
Vincenza Spallone
Research17 Oct 2019
Journal of Human Hypertension

Volume: 34, P: 495-504
Investigating the genetic basis of salt-tolerance in common bean: a genome-wide association study at the early vegetative stage

Lorenzo Raggi
Leonardo Caproni
Valeria Negri
ResearchOpen Access04 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia

Matteo Allegretti
Maria Rosaria Ricciardi
Agostino Tafuri
ResearchOpen Access17 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers

Concetta Di Mauro
Roberta Rosa
Roberto Bianco
ResearchOpen Access25 Apr 2017
British Journal of Cancer

Volume: 116, P: 1425-1435
A molecular barcode and web-based data analysis tool to identify imported Plasmodium vivax malaria

An online, amendable classifier for detecting malaria parasite country of origin from genomic data is developed using a machine learning approach.

Hidayat Trimarsanto
Roberto Amato
Sarah Auburn
ResearchOpen Access23 Dec 2022
Communications Biology

Volume: 5, P: 1-10
Inflammatory biomarkers and pendelluft magnitude in ards patients transitioning from controlled to partial support ventilation

Rodrigo A. Cornejo
Daniel H. Arellano
Nivia R. Estuardo
ResearchOpen Access23 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
PPARγ Activation Attenuates Opioid Consumption and Modulates Mesolimbic Dopamine Transmission

Giordano de Guglielmo
Miriam Melis
Roberto Ciccocioppo
Research14 Sept 2014
Neuropsychopharmacology

Volume: 40, P: 927-937
Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia

Alfred Amambua-Ngwa
David Jeffries
Umberto D’Alessandro
ResearchOpen Access26 Jun 2018
Scientific Reports

Volume: 8, P: 1-10
Selenium maintains cytosolic Ca²⁺homeostasis and preserves germination rates of maize pollen under H₂O₂-induced oxidative stress

Alberto Marco Del Pino
Marcello Guiducci
Carlo Alberto Palmerini
ResearchOpen Access18 Sept 2019
Scientific Reports

Volume: 9, P: 1-9
High HIV-1 diversity in immigrants resident in Italy (2008–2017)

Maria Teresa Maggiorella
Nunzia Sanarico
Serena Dell’Isola
ResearchOpen Access24 Feb 2020
Scientific Reports

Volume: 10, P: 1-14
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett
Joe Grove
Emma C. Thomson
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Microbiology

Volume: 7, P: 1709
Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors

Concetta Di Mauro
Ada Pesapane
Roberto Bianco
ResearchOpen Access24 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe

Hadis Honarvar
Enrica Calce
Stefania De Luca
ResearchOpen Access14 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
Histone Modifications in a Mouse Model of Early Adversities and Panic Disorder: Role for Asic1 and Neurodevelopmental Genes

Davide Cittaro
Valentina Lampis
Marco Battaglia
ResearchOpen Access28 Apr 2016
Scientific Reports

Volume: 6, P: 1-10
Local 5,7-Dihydroxytryptamine Lesions of Rat Amygdala: Release of Punished Drinking, Unaffected Plus-Maze Behavior and Ethanol Consumption

Wolfgang Sommer
Christian Moller
Markus Heilig
Research01 Apr 2001
Neuropsychopharmacology

Volume: 24, P: 430-440
Growth arrest and a persister state enable resistance to osmotic shock and facilitate dissemination of Vibrio cholerae

Cecilia A Silva-Valenzuela
David W Lazinski
Andrew Camilli
Research25 Jul 2017
The ISME Journal

Volume: 11, P: 2718-2728
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17

Search

Filter By:

Search

Quick links