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Showing 1–13 of 13 results
Advanced filters: Author: Robyn P. Araujo Clear advanced filters
  • At the molecular level, the evolution of life is driven by the generation and diversification of adaptation mechanisms. Here Araujo and Liotta identify definitive and universal structural requirements for adaptation via intermolecular interactions.

    • Robyn P. Araujo
    • Lance A. Liotta
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12
  • Exome sequencing of 851 trios from more than 2,500 individuals finds 187 genes with de novo mutations that contribute to meningomyelocele (spina bifida) and highlights critical pathways required for neural tube closure.

    • Yoo-Jin Jiny Ha
    • Ashna Nisal
    • Joseph G. Gleeson
    Research
    Nature
    Volume: 641, P: 419-426
  • Laser capture microdissection is a technique that uses a highly precise laser to isolate and collect specific cells from a tissue sample. In this Primer, Liotta et al. discuss the use of laser capture microdissection in clinical research and its potential in future personalized therapies.

    • Lance A. Liotta
    • Thomas P. Conrads
    • Emanuel F. Petricoin
    Reviews
    Nature Reviews Methods Primers
    Volume: 5, P: 1-23
  • Studying rare genetic changes that arose as an infectious bacterium spread between lab mice, here the authors show that using the relative abundance of any changes rather than just whether they occurred can more precisely identify who likely infected who.

    • Madikay Senghore
    • Hannah Read
    • Siouxsie Wiles
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12
  • Robust perfect adaptation (RPA), the ability of a system to return to its pre-stimulus state in the presence of a new signal, enables organisms to respond to further changes in stimuli. Here, the authors identify the modular structure of the full set of network topologies that can confer RPA on complex networks.

    • Robyn P. Araujo
    • Lance A. Liotta
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12
  • The Amazon rainforest is dominated by relatively few tree species, yet the degree to which this hyperdominance influences carbon cycling remains unknown. Here, the authors analyse 530 forest plots and show that ∼1% of species are responsible for 50% of the aboveground carbon storage and productivity.

    • Sophie Fauset
    • Michelle O. Johnson
    • Oliver L. Phillips
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-9
  • To fully realize the potential of molecularly targeted therapies for cancer and other human diseases, a new level of knowledge about the complex cellular control circuitry is required. Here, the authors explore mathematical paradigms that facilitate the design of network-targeted anticancer drugs.

    • Robyn P. Araujo
    • Lance A. Liotta
    • Emanuel F. Petricoin
    Reviews
    Nature Reviews Drug Discovery
    Volume: 6, P: 871-880