AMP-activated protein kinase (AMPK) is important for mitosis and epithelial cell polarity and these effects are a result of direct phosphorylation of non-muscle myosin regulatory light chain by AMPK. This is the first study reporting AMPK deletion in an entire organism and highlights the physiological function of this kinase.
- Jun Hee Lee
- Hyongjong Koh
- Jongkyeong Chung