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Showing 1–4 of 4 results

Advanced filters: Author: Roger H. Caothien Clear advanced filters

Immunization of hu-PBL–SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries

Michel A. Duchosal
Sabine A. Eming
Dennis R. Burton
Research16 Jan 1992
Nature

Volume: 355, P: 258-262
Integration of innate immune signalling by caspase-8 cleavage of N4BP1

NEDD4-binding protein 1 (N4BP1) is identified as a suppressor of cytokine production that is inactivated by caspase-8, which provides insight into the mechanisms underlying the immunodeficiency caused by mutations in FADD and caspase-8.

Alexander D. Gitlin
Klaus Heger
Vishva M. Dixit
Research24 Sept 2020
Nature

Volume: 587, P: 275-280
LRRC15⁺ myofibroblasts dictate the stromal setpoint to suppress tumour immunity

LRRC15-positive cancer-associated fibroblasts constitute a pivotal axis in tumorigenesis and are potential therapeutic targets to improve responses to immune checkpoint blockade.

Akshay T. Krishnamurty
Justin A. Shyer
Shannon J. Turley
ResearchOpen Access28 Sept 2022
Nature

Volume: 611, P: 148-154
Cross-tissue organization of the fibroblast lineage

Single-cell and genetic tools are used to characterize the diversity of fibroblasts across healthy and perturbed tissues in mice and humans.

Matthew B. Buechler
Rachana N. Pradhan
Shannon. J. Turley
Research12 May 2021
Nature

Volume: 593, P: 575-579