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Showing 1–2 of 2 results
Advanced filters: Author: Romain Guilbert Clear advanced filters

  • Nonsense mutations can be corrected by several molecules that activate readthrough of premature termination codon. Here, the authors report that 2,6-diaminopurine efficiently corrects UGA nonsense mutations with no significant toxicity.

    • Carole Trzaska
    • Séverine Amand
    • Fabrice Lejeune
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Bouyer et al. report that the new permeation pathways (NPP), responsible of modulating erythrocyte permeability to diverse solutes and considered only to be in pathogenic asexual stages of P. falciparum, are also active in erythrocytes infected with immature gametocytes and this activity declines with gametocyte maturation. NPPs are regulated by the cAMP signalling cascade, and the decrease in cAMP levels in mature stages slows NPP activity.

    • Guillaume Bouyer
    • Daniela Barbieri
    • Catherine Lavazec
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-10