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Showing 1–7 of 7 results
Advanced filters: Author: Romy Wichmann Clear advanced filters

  • In mouse brain, neurotensin released into the basolateral amygdala by neurons in the paraventricular nucleus of the thalamus assigns positive or negative valence during associative learning.

    • Hao Li
    • Praneeth Namburi
    • Kay M. Tye
    Research
    Nature
    Volume: 608, P: 586-592

  • Fatal Ebola virus disease is characterized by a high proportion of CD4+ and CD8+ T cells expressing the inhibitory molecules CTLA-4 and PD-1, correlating with high virus load; individuals who survive the infection exhibit lower expression of these inhibitory molecules and generate Ebola-specific CD8+ T cells, suggesting that dysregulation of the T cell response is a key component of Ebola virus disease pathophysiology.

    • Paula Ruibal
    • Lisa Oestereich
    • César Muñoz-Fontela
    Research
    Nature
    Volume: 533, P: 100-104

  • Neurons in the basolateral amygdala projecting to canonical fear or reward circuits undergo opposing changes in synaptic strength following fear or reward conditioning, and selectively activating these projection-target-defined neural populations causes either negative or positive reinforcement, respectively.

    • Praneeth Namburi
    • Anna Beyeler
    • Kay M. Tye
    Research
    Nature
    Volume: 520, P: 675-678