Recent studies have shown that nuclear export of mRNAs, which is a crucial step in the regulation of gene expression, can be selective in mammalian cells. Selective transport involves transcription-export complexes TREX and TREX-2 and controls biological processes such as DNA repair, haematopoiesis, proliferation and maintenance of pluripotency.
- Vihandha O. Wickramasinghe
- Ronald A. Laskey
