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Showing 1–12 of 12 results
Advanced filters: Author: Ronen Zaidel-Bar Clear advanced filters

  • How different integrin receptors for the same extracellular ligand transduce distinct cellular responses is unclear. The characterization of the class-specific adhesomes of β1 and αV integrins now shows that whereas αV integrins promote unbranched actin polymerization, β1 integrins induce myosin-II-dependent contractility, and both integrin subtypes synergistically mediate rigidity sensing.

    • Ronen Zaidel-Bar
    News & Views
    Nature Cell Biology
    Volume: 15, P: 575-577

  • The Chloride Intracellular Channel (CLIC) protein family is highly conserved, yet their function remains a matter of ongoing research. Here, authors reveal their ability to facilitate membrane fusion, shedding light on their physiological role.

    • Bar Manori
    • Alisa Vaknin
    • Yoni Haitin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Classical actin-dependent, integrin-mediated cell–matrix adhesions disassemble before mitotic rounding. Yet, to transmit positional information and facilitate daughter-cell separation, dividing cells maintain connections to the matrix. A previously unidentified class of actin-independent integrin adhesions may fulfil this task.

    • Ronen Zaidel-Bar
    News & Views
    Nature Cell Biology
    Volume: 20, P: 1233-1235

  • Germline cells in many species are fused to form a syncytium but the mechanics behind the maintenance of these structures are poorly defined. Here, the authors propose an inner contractile actomyosin corset provides a supportive framework to maintain germline architecture in C. elegans.

    • Agarwal Priti
    • Hui Ting Ong
    • Ronen Zaidel-Bar
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15

  • Bertocchi and colleagues describe the organization of cadherin-based adhesions using super-resolution microscopy. They find that α-catenin is important for vinculin localization and observe a conformational change in vinculin following its activation.

    • Cristina Bertocchi
    • Yilin Wang
    • Pakorn Kanchanawong
    Research
    Nature Cell Biology
    Volume: 19, P: 28-37

  • Using structured illumination microscopy, Beach et al. and Hu et al. visualize the assembly of myosin II filaments in cells, describing a filament-partitioning mechanism, and long-range self-organization of filaments, respectively.

    • Shiqiong Hu
    • Kinjal Dasbiswas
    • Alexander D. Bershadsky
    Research
    Nature Cell Biology
    Volume: 19, P: 133-141