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Showing 1–3 of 3 results

Advanced filters: Author: Rongting Huang Clear advanced filters

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone

Somatic copy number alterations (CNAs) of parts of the genome can contribute to the development and progression of various cancers. Here, the authors present a statistical method to detect clonal and allele-specific CNAs from single-cell RNA-sequencing data with high robustness.

Rongting Huang
Xianjie Huang
Yuanhua Huang
ResearchOpen Access06 Aug 2024
Nature Communications

Volume: 15, P: 1-16
MQuad enables clonal substructure discovery using single cell mitochondrial variants

Mitochondrial variants are informative endogenous barcodes for clonal substructure. Here, the authors developed a computational method MQuad to effectively detect these clonal informed mtDNA variants from single-cell RNA, DNA or ATAC sequencing data.

Aaron Wing Cheung Kwok
Chen Qiao
Yuanhua Huang
ResearchOpen Access08 Mar 2022
Nature Communications

Volume: 13, P: 1-10
Effects of various wet environments on the characteristics of the dust cake deposited on the surface of filter media

Shihang Li
Yihan Lin
Rongting Huang
ResearchOpen Access10 Oct 2023
Scientific Reports

Volume: 13, P: 1-10