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Signal Transduction and Targeted Therapy (1)
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Showing 1–4 of 4 results

Advanced filters: Author: Rongyang Gao Clear advanced filters

RECQL4 promotes the malignant progression of lung adenocarcinoma through the YBX1/G3BP1-mediated NF-κB signaling pathway

Rongyang Li
Wenhao Yu
Cun Gao
ResearchOpen Access09 Jan 2026
Cell Death Discovery

Volume: 12, P: 1-13
The structural basis of the activation and inhibition of DSR2 NADase by phage proteins

This research shows how the bacterial protein DSR2, which protects against phage infection by degrading NAD⁺, is activated by phage protein TTP and inhibited by phage protein DSAD1 through cryo-EM studies and biochemical assays.

Ruiwen Wang
Qi Xu
Faxiang Li
ResearchOpen Access23 Jul 2024
Nature Communications

Volume: 15, P: 1-12
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury

Activation of the Nrf2/HO-1 antioxidant signaling pathway exacerbates cholestatic liver injury due to excessive accumulation of bilirubin, rather than exerting a protective effect as in non-cholestatic liver injury.

Yi Wang
Xiaolong Fu
Shaoyu Zhou
ResearchOpen Access23 May 2024
Communications Biology

Volume: 7, P: 1-17
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages

Dapeng Zhang
Rongchen Shi
Hongming Miao
ResearchOpen Access27 Mar 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-13