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Showing 1–6 of 6 results

Advanced filters: Author: Rory Munro Clear advanced filters

Integrated structural dynamics uncover a new B₁₂ photoreceptor activation mode

Spatiotemporal insight into photoactivation of the prototypical B₁₂ photoreceptor CarH is revealed across nine orders of magnitude in time, identifying a transient adduct that distinguishes it from thermally activated B₁₂ enzymes.

Ronald Rios-Santacruz
Harshwardhan Poddar
Giorgio Schirò
Research04 Feb 2026
Nature

Volume: 650, P: 1045-1052
Emotion processing and electrodermal activity in young people who self-harm

Young individuals with a history of self-harm exhibit heightened electrodermal activity in response to neutral and stress-related stimuli, extending our understanding of the biophysiological factors for self-harm vulnerability.

Karen Wetherall
Seonaid Cleare
Rory C. O’Connor
ResearchOpen Access05 Nov 2025
Nature Mental Health

Volume: 3, P: 1374-1383
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

Here, using cryo-EM and smFRET, Henderson et al. show how tryptophan 571 in the HIV-1 Env acts as a conformational switch during receptor-mediated viral entry and design HIV-1 Env proteins that cannot undergo conformational changes. This has important implications for HIV-1 vaccine design.

Rory Henderson
Maolin Lu
S. Munir Alam
ResearchOpen Access24 Jan 2020
Nature Communications

Volume: 11, P: 1-14
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors

Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling within 24 hours.

Areeba Patel
Kirsten Göbel
Felix Sahm
ResearchOpen Access25 Mar 2025
Nature Medicine

Volume: 31, P: 1567-1577
Dynamic, adaptive sampling during nanopore sequencing using Bayesian experimental design

Nanopore selective sequencing with real-time decision updates mitigates coverage bias.

Lukas Weilguny
Nicola De Maio
Nick Goldman
ResearchOpen Access02 Jan 2023
Nature Biotechnology

Volume: 41, P: 1018-1025
Readfish enables targeted nanopore sequencing of gigabase-sized genomes

A nanopore sequencer achieves selective sequencing of any region in the human genome.

Alexander Payne
Nadine Holmes
Matthew Loose
Research30 Nov 2020
Nature Biotechnology

Volume: 39, P: 442-450