Nature Search

Mode of Production of Chromosome Abnormalities by the Nitrogen Mustards The Possible Role of Cross-Linking

R. J. GOLDACRE
A. LOVELESS
W. C. J. ROSS
Research30 Apr 1949
Nature

Volume: 163, P: 667-669
Effects upon tumours of Various Haloalkylarylamines

ALEXANDER HADDOW
G. A. R. KON
W. C. J. ROSS
Research20 Nov 1948
Nature

Volume: 162, P: 824-825
CellSAM: a foundation model for cell segmentation

CellSAM uses an object detector, CellFinder, to detect cells and prompt the Segment Anything Model (SAM) to generate segmentations. This universal model achieves human-level performance across a range of bioimaging data encompassing mammalian cells, yeast and bacteria.

Markus Marks
Uriah Israel
David Van Valen
ResearchOpen Access08 Dec 2025
Nature Methods

Volume: 22, P: 2585-2593
Association of Detectable Antibodies produced by Haemonchus spp. Infections in Cattle, with Serum Globulin Fractions

J. G. ROSS
Research10 Jun 1961
Nature

Volume: 190, P: 1019-1020
Extensive fluvial surfaces at the East Antarctic margin have modulated ice-sheet evolution

Extensive flat surfaces observed beneath the East Antarctic Ice Sheet margin were formed by fluvial erosion and have modulated the ice-sheet response to climate change, according to an analysis of radio-echo sounding data.

Guy J. G. Paxman
Stewart S. R. Jamieson
Martin J. Siegert
ResearchOpen Access11 Jul 2025
Nature Geoscience

Volume: 18, P: 724-731
Ice-forming Nuclei in the Atmosphere

J. B. STEWART
I. Ross
CATHERINE M. STEVENSON
Research10 Sept 1966
Nature

Volume: 211, P: 1164
An ancient river landscape preserved beneath the East Antarctic Ice Sheet

Using satellite and survey data, an ancient river landscape 300 km wide has been discovered buried and preserved beneath the ice in East Antarctica. It has likely survived largely intact for up to 34 million years since before ice sheet growth.

Stewart S. R. Jamieson
Neil Ross
Martin J. Siegert
ResearchOpen Access24 Oct 2023
Nature Communications

Volume: 14, P: 1-12
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
ResearchOpen Access09 Oct 2024
Nature

Volume: 635, P: 462-471
Non-steroidal anti-inflammatory drugs and bladder cancer prevention

J E Castelao
J-M Yuan
R K Ross
ResearchOpen Access07 Mar 2000
British Journal of Cancer

Volume: 82, P: 1364-1369
Fractional allele loss data indicate distinct genetic populations in the development of non-small-cell lung cancer

JK Field
EM Neville
RJ Donnelly
Research01 Dec 1996
British Journal of Cancer

Volume: 74, P: 1968-1974
Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice

Kiran Chada
Jeanne Magram
Frank Costantini
Research28 Mar 1985
Nature

Volume: 314, P: 377-380
GH, IGF-I and binding proteins in altered nutritional states

RJM Ross
Research24 Jul 2000
International Journal of Obesity

Volume: 24, P: S92-S95
Cumulates from strongly depleted mid-ocean-ridge basalt

Kent Ross
Don Elthon
Research28 Oct 1993
Nature

Volume: 365, P: 826-829
Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
Amendments and CorrectionsOpen Access27 Feb 2025
Nature

Volume: 639, P: E19
Regular use of analgesics is a risk factor for renal cell carcinoma

M Gago-Dominguez
J-M Yuan
M C Yu
ResearchOpen Access10 Sept 1999
British Journal of Cancer

Volume: 81, P: 542-548
Estimation of the Survival-Rate of Anopheline Mosquitoes in Nature

G. DAVIDSON
Research23 Oct 1954
Nature

Volume: 174, P: 792-793
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

Marja J. C. Steenman
Shirley Rainier
Andrew P. Feinberg
Research01 Jul 1994
Nature Genetics

Volume: 7, P: 433-439
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy

The relationship between pathogenic germline variation, clonal hematopoiesis (CH) and risk of hematologic malignancy is explored in 731,835 individuals across 6 cohorts. Carriers of variants in certain genes show distinct patterns of CH and increased risk of CH progression to malignancy.

Jie Liu
Duc Tran
Kelly L. Bolton
ResearchOpen Access15 Jul 2025
Nature Genetics

Volume: 57, P: 1872-1880
Seasonal variations in the diagnosis of childhood cancer in the United States

J A Ross
R K Severson
L L Robison
ResearchOpen Access10 Sept 1999
British Journal of Cancer

Volume: 81, P: 549-553
Persistent Latent Infection of Human Embryonic Cells with Reovirus Type 3

T. M. BELL
M. G. R. ROSS
Research22 Oct 1966
Nature

Volume: 212, P: 412-414
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Measuring the semantic priming effect across many languages

In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

Erin M. Buchanan
Kelly Cuccolo
Savannah C. Lewis
Research24 Sept 2025
Nature Human Behaviour

Volume: 10, P: 182-201
Expresssion of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells

LA Doyle
DD Ross
CA Schiffer
Research01 Jan 1995
British Journal of Cancer

Volume: 71, P: 52-58
Pretrained transformers applied to clinical studies improve predictions of treatment efficacy and associated biomarkers

A framework for building foundation models using diverse patient data can enhance survival prediction and provide interpretable insights into treatment response. Here, the authors show that their approach outperforms existing methods while integrating generative and interpretable modules to reveal clinically relevant biological insights.

Gustavo Arango-Argoty
Elly Kipkogei
Etai Jacob
ResearchOpen Access01 Mar 2025
Nature Communications

Volume: 16, P: 1-18
p53 gene aberrations in non-small-cell lung carcinomas from a smoking population

T Liloglou
H Ross
JK Field
Research01 Apr 1997
British Journal of Cancer

Volume: 75, P: 1119-1124
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Vestiges of a beginning?

Stuart Ross Taylor
News & Views31 Dec 1992
Nature

Volume: 360, P: 710-711
Tubulin requires an accessory protein for self assembly into microtubules

ROBERT A. B. KEATES
ROSS H. HALL
Research02 Oct 1975
Nature

Volume: 257, P: 418-421
The future of obesity reduction: beyond weight loss

Until recently, weight loss has been viewed as the principal determinant of success in obesity reduction. This Review details a growing body of evidence that links adoption of a healthy lifestyle (but minimal or no weight loss) with appreciable reductions in obesity, in particular abdominal obesity, and related cardiometabolic risk.

Robert Ross
Alison J. Bradshaw
Reviews07 May 2009
Nature Reviews Endocrinology

Volume: 5, P: 319-325
Developmental regulation of CRD-BP, an RNA-binding protein that stabilizes c-myc mRNA in vitro

Peter Leeds
Betsy T Kren
Jeffrey Ross
Research20 Mar 1997
Oncogene

Volume: 14, P: 1279-1286
Compassionate access to virus-specific T cells for adoptive immunotherapy over 15 years

Adoptive T-cell immunotherapy offers promise to patients who are resistant to standard anti-viral strategies. Here the authors describe clinical observations in patients with viral complications treated with adoptive immunotherapy over the last 15 years.

Michelle A. Neller
George R. Ambalathingal
Rajiv Khanna
ResearchOpen Access03 Dec 2024
Nature Communications

Volume: 15, P: 1-12
Pre-operative stereotactic radiosurgery and peri-operative dexamethasone for resectable brain metastases: a two-arm pilot study evaluating clinical outcomes and immunological correlates

Radiation and steroid dosing can affect the immune composition of brain metastasis (BM). The authors have designed a pilot study of pre-operative stereotactic radiosurgery with low or high dose of peri-operative dexamethasone for resectable brain metastases, here reporting clinical outcomes and characterization of intratumor TCF1+ CD8+ stem-like T cell immune niches in the brain.

Caroline S. Jansen
Meghana S. Pagadala
Zachary S. Buchwald
ResearchOpen Access14 Oct 2024
Nature Communications

Volume: 15, P: 1-15
The effects of 118 years of industrial fishing on UK bottom trawl fisheries

Fish stocks in the ocean are known to be under threat. Here, using government data describing commercial fish landings, Thurstan and colleagues show that these stocks began to decline rapidly in the 1970s.

Ruth H. Thurstan
Simon Brockington
Callum M. Roberts
Research04 May 2010
Nature Communications

Volume: 1, P: 1-6
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction

Pooled and sex-specific genome-wide association analyses identify new risk loci for restless legs syndrome and candidates for drug repurposing. Machine learning models combining genetic and other information show improved risk prediction performance.

Barbara Schormair
Chen Zhao
Juliane Winkelmann
ResearchOpen Access05 Jun 2024
Nature Genetics

Volume: 56, P: 1090-1099
Detection of varicella-zoster virus DNA in ocular samples from patients with uveitis but no cutaneous eruption

P Stavrou
S M Mitchell
P I Murray
Research01 Nov 1994
Eye

Volume: 8, P: 684-687
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

R.E. Tanzi
K. Petrukhin
T.C. Gilliam
Research01 Dec 1993
Nature Genetics

Volume: 5, P: 344-350
B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

B cells are playing an active role in shaping the tumour immune microenvironment and the anti-tumour immune response in melanomas. Here authors show that intra-tumoral B cells are aberrantly activated and produce antibodies that are potentially autoreactive.

Silvia Crescioli
Isabel Correa
Sophia N. Karagiannis
ResearchOpen Access08 Jun 2023
Nature Communications

Volume: 14, P: 1-21
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
High treatment-related mortality in cardiac amyloid patients undergoing autologous stem cell transplant

N Saba
DM Sutton
AK Stewart
Research05 Oct 1999
Bone Marrow Transplantation

Volume: 24, P: 853-855
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial

Glucocorticoids prescribed to limit inflammation, have significant adverse effects. Here the authors show that co-administration of AZD4017 with prednisolone in men is a potential strategy to limit adverse glucocorticoid effects.

Nantia Othonos
Riccardo Pofi
Jeremy W. Tomlinson
ResearchOpen Access23 Feb 2023
Nature Communications

Volume: 14, P: 1-12
A ¹³C-DEPLETED INFANT FORMULA USEFUL FOR METABOLIC STUDIES

Thomas W Boutton
Judy M Hopkinson
Peter D Klein
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 264
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1

Mabe et al. find that GD2 levels correlate with lineage plasticity in neuroblastoma and identify ST8SIA1 as the key enzyme in GD2 synthesis. EZH2 inhibition in mesenchymal neuroblastoma cells elevates ST8SIA1, synergizing with anti-GD2 antibodies.

Nathaniel W. Mabe
Min Huang
Robbie G. Majzner
Research11 Jul 2022
Nature Cancer

Volume: 3, P: 976-993
The contribution of X-linked coding variation to severe developmental disorders

Developmental disorders (DDs) are more prevalent in males, thought to be due to X-linked genetic variation. Here, the authors investigate the burden of X-linked coding variants in 11,044 DD patients, showing that this contributes to ~6% of both male and female cases and therefore does not solely explain male bias in DDs.

Hilary C. Martin
Eugene J. Gardner
Matthew E. Hurles
ResearchOpen Access27 Jan 2021
Nature Communications

Volume: 12, P: 1-13
Cingulin, a new peripheral component of tight junctions

Sandra Citi
Helena Sabanay
John Kendrick-Jones
Research19 May 1988
Nature

Volume: 333, P: 272-276
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Evidence for 28 genetic disorders discovered by combining healthcare and research data

By integrating healthcare and exome-sequencing data from parent–offspring trios of patients with developmental disorders, 28 genes that had not previously been associated with developmental disorders were identified.

Joanna Kaplanis
Kaitlin E. Samocha
Kyle Retterer
Research14 Oct 2020
Nature

Volume: 586, P: 757-762
Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome

Gabrielle Olley
Morad Ansari
David R. FitzPatrick
Amendments and Corrections03 Jun 2019
Nature Genetics

Volume: 51, P: 1192

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