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Showing 1–2 of 2 results
Advanced filters: Author: Rouaa Ben Chaabene Clear advanced filters

  • Host cell invasion by Toxoplasma gondii depends on the heavily phosphorylated RON complex, but the relevance and regulation of these modifications are not understood. Here, the authors identify the kinase RON13 as a key virulence factor, determine its structure and show that it phosphorylates the RON complex.

    • Gaëlle Lentini
    • Rouaa Ben Chaabene
    • Dominique Soldati-Favre
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17

  • Sergey Nikolaev, Stylianos Antonarakis and colleagues analyze the genetic architecture of 293 basal cell carcinomas (BCCs) and characterize their mutational landscape. They observe UV signature mutations and identify new driver mutations in MYCN, PTPN14 and LATS1 in BCC.

    • Ximena Bonilla
    • Laurent Parmentier
    • Sergey I Nikolaev
    Research
    Nature Genetics
    Volume: 48, P: 398-406