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Showing 1–3 of 3 results
Advanced filters: Author: Rubén Hervás Clear advanced filters

  • The molecular mechanisms of how small changes in the degree of inclusion of a neuron-specific microexon in CPEB4 lead to dominant-negative effects in the expression of genes associated with autism spectrum disorder are identified.

    • Carla Garcia-Cabau
    • Anna Bartomeu
    • Xavier Salvatella
    ResearchOpen Access
    Nature
    Volume: 637, P: 496-503

  • In this work, the authors show that metamorphism in the post-translationally modified TDP-43 prion-like domain encodes determinants that command mechanisms with major relevance in disease and stress the relevance of post-translationally modified chains as the targets for disease intervention.

    • Jaime Carrasco
    • Rosa Antón
    • Javier Oroz
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15