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Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Here they identify Tex10 as a critical regulator of male fertility and germ cell development. By fine-tuning Wnt signaling, Tex10 promotes spermatogenesis and PGC differentiation, offering potential therapeutic insights for treating male infertility.

Feifei Yuan
Jihong Yang
Jianlong Wang
ResearchOpen Access23 Feb 2025
Nature Communications

Volume: 16, P: 1-22

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Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

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