Nature Search

Yeast metabolism adaptation for efficient terpenoids synthesis via isopentenol utilization

The isopentenol utilization (IU) pathway has been reported as an alternative synthetic route for terpenoid synthesis, but isopentenol inhibits energy metabolism in baker’s yeast. Here, the authors solve the problem by replacing the mevalonate pathway with the IU pathway for growth-coupled squalene, β-carotene, and limonene production.

Guangjian Li
Hui Liang
Wen-Yong Lou
ResearchOpen Access13 Nov 2024
Nature Communications

Volume: 15, P: 1-12
High energy resolution CsPbBr₃ alpha particle detector with a full-customized readout application specific integrated circuit

By developing a synergistic strategy of thinning the perovskite crystal, employing Schottky electrode and full-customised readout application specific integrated circuit to supress dark current and electronic noise, the authors report an energy resolution of 1.1% for perovskite α-particle detector.

Xin Zhang
Ruichen Bai
Yadong Xu
ResearchOpen Access27 Jul 2024
Nature Communications

Volume: 15, P: 1-9
Flexible multichannel electrodes for acute recording in nonhuman primates

Yang Wang
Qifan Wang
Weihua Pei
ResearchOpen Access20 Jul 2023
Microsystems & Nanoengineering

Volume: 9, P: 1-8
Next-generation sequencing-based molecular diagnosis of 12 inherited retinal disease probands of Uyghur ethnicity

Abulikemu Tajiguli
Mingchu Xu
Haji Akber Aisa
ResearchOpen Access09 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
The phenotypic variability of HK1-associated retinal dystrophy

Zhisheng Yuan
Baiyu Li
Rui Chen
ResearchOpen Access01 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Next-generation sequencing-based molecular diagnosis of 35 Hispanic retinitis pigmentosa probands

Qi Zhang
Mingchu Xu
Rui Chen
ResearchOpen Access06 Sept 2016
Scientific Reports

Volume: 6, P: 1-8
Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration

Rui Chen and colleagues identify mutations in NMNAT1 as a new cause of Leber congenital amaurosis. They further show that all examined individuals with NMNAT1 mutations have macular colobomas, a condition marked by severe degeneration of the central retina.

Robert K Koenekoop
Hui Wang
Rui Chen
Research29 Jul 2012
Nature Genetics

Volume: 44, P: 1035-1039
Ecological inferences on invasive carp survival using hydrodynamics and egg drift models

Ruichen Xu
Duane C. Chapman
Binbin Wang
ResearchOpen Access25 Apr 2024
Scientific Reports

Volume: 14, P: 1-15
NGS-based Molecular diagnosis of 105 eyeGENE^® probands with Retinitis Pigmentosa

Zhongqi Ge
Kristen Bowles
Rui Chen
ResearchOpen Access15 Dec 2015
Scientific Reports

Volume: 5, P: 1-9
Spectral imaging with deep learning

This review categorizes deep-learning-based computational spectral imaging methods and provides insight into amplitude, phase, and wavelength-based light encoding strategies for deep-learning spectral reconstruction.

Longqian Huang
Ruichen Luo
Xiang Hao
ReviewsOpen Access16 Mar 2022
Light: Science & Applications

Volume: 11, P: 1-19

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Yeast metabolism adaptation for efficient terpenoids synthesis via isopentenol utilization

High energy resolution CsPbBr₃ alpha particle detector with a full-customized readout application specific integrated circuit

Flexible multichannel electrodes for acute recording in nonhuman primates

Next-generation sequencing-based molecular diagnosis of 12 inherited retinal disease probands of Uyghur ethnicity

The phenotypic variability of HK1-associated retinal dystrophy

Next-generation sequencing-based molecular diagnosis of 35 Hispanic retinitis pigmentosa probands

Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration

Ecological inferences on invasive carp survival using hydrodynamics and egg drift models

NGS-based Molecular diagnosis of 105 eyeGENE^® probands with Retinitis Pigmentosa

Spectral imaging with deep learning

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