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Showing 1–50 of 63 results

Advanced filters: Author: Ruiqi Yu Clear advanced filters

Engineered thoracic spinal cord organoids for transplantation after spinal cord injury

Thoracic vertebral segment-specific spinal cord organoids transplanted in a spinal cord injury mouse model can precisely match the transplantation site, establish synaptic connections, enhance in vivo neuroelectric conduction and restore motor function.

Yanjing Zhu
Ruiqi Huang
Rongrong Zhu
ResearchOpen Access24 Oct 2025
Nature Biomedical Engineering

P: 1-21
DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning

A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

Daya Guo
Dejian Yang
Zhen Zhang
ResearchOpen Access17 Sept 2025
Nature

Volume: 645, P: 633-638
Expression of p53 gene in hepatocellular carcinomas induced by aflatoxin B1 with or without human hepatitis B virus in tree shrews

Jianjia Su
Guozhong Qin
Prabhakar D Lotlikar
ResearchOpen Access01 Sept 1997
Experimental & Molecular Medicine

Volume: 29, P: 177-182
Streamlining evidence based clinical recommendations with large language models

Dubai Li
Nan Jiang
Jingsong Li
ResearchOpen Access22 Dec 2025
npj Digital Medicine

Volume: 8, P: 1-19
Catalytic refining lignin into toluene over atomically dispersed Cu/Ni dual sites

Lignin refining continues to face major challenges in achieving selective depolymerization and breaking resistant C–C bonds. In this work, the authors design a robust atomically dispersed Cu/Ni-SA@HNC catalyst that enables highly selective hydrogenolysis of lignin and model compounds through an unconventional pathway involving preferential Cα–Cβ bond cleavage in β-O-4 linkages.

Xin Zhao
Changzhi Li
Tao Zhang
ResearchOpen Access26 Aug 2025
Nature Communications

Volume: 16, P: 1-12
Photosymbiosis shaped animal genome architecture and gene evolution as revealed in giant clams

The Tridacna maxima genome reveals how long-term symbiosis drives evolution, highlighting climate-driven population shifts, immune gene adaptations, and transposable element expansions shaping its genetic landscape.

Ruiqi Li
Carlos Leiva
Jingchun Li
ResearchOpen Access04 Jan 2025
Communications Biology

Volume: 8, P: 1-12
Transcriptome-wide profiling and quantification of N⁶-methyladenosine by enzyme-assisted adenosine deamination

N⁶-methyladenosine is mapped at single-base resolution in as few as ten cells.

Yu-Lan Xiao
Shun Liu
Weixin Tang
Research02 Jan 2023
Nature Biotechnology

Volume: 41, P: 993-1003
Author Correction: Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels

Wang Zheng
Xiaoyong Yang
Xing-Zhen Chen
Amendments and CorrectionsOpen Access26 Mar 2019
Nature Communications

Volume: 10, P: 1
RBFOX2 recognizes N⁶-methyladenosine to suppress transcription and block myeloid leukaemia differentiation

Dou, Xiao, Shen, Wang et al. show that RBFOX2 recognizes m⁶A on chromatin-associated RNAs and recruits RBM15, YTHDC1 and PRC2 to facilitate transcription suppression. Inhibition of the axis exerts anti-leukaemic effects.

Xiaoyang Dou
Yu Xiao
Chuan He
ResearchOpen Access28 Aug 2023
Nature Cell Biology

Volume: 25, P: 1359-1368
Genetic risk factors underlying white matter hyperintensities and cortical atrophy

White matter hyperintensities are linked to cortical atrophy, a key feature in dementia. Here, the authors identify loci associated with cortical atrophy related to white matter hyperintensities, which involve vascular and neuronal processes.

Yash Patel
Jean Shin
Zdenka Pausova
ResearchOpen Access04 Nov 2024
Nature Communications

Volume: 15, P: 1-11
A genome-wide association analysis reveals new pathogenic pathways in gout

Genome-wide association analysis of gout and urate identifies 148 new loci, implicating biological pathways and prioritizing candidate genes involved in inflammatory processes.

Tanya J. Major
Riku Takei
Tony R. Merriman
Research15 Oct 2024
Nature Genetics

Volume: 56, P: 2392-2406
High-sensitivity, high-speed, broadband mid-infrared photodetector enabled by a van der Waals heterostructure with a vertical transport channel

Here, the authors report the realization of room-temperature broadband mid-infrared detectors based on a van der Waals heterostructure with a vertical transport channel, exhibiting specific detectivity and response times comparable or superior to those of commercial cooled HgCdTe photodetectors.

Jianfeng Wu
Jialin Zhang
Zhenhua Ni
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-10
Stroke genetics informs drug discovery and risk prediction across ancestries

A cross-ancestry meta-analysis of genome-wide association studies identifies association signals for stroke and its subtypes at 89 (61 new) independent loci, reveals putative causal genes, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as potential drug targets, and provides cross-ancestry integrative risk prediction.

Aniket Mishra
Rainer Malik
Stephanie Debette
ResearchOpen Access30 Sept 2022
Nature

Volume: 611, P: 115-123
Construction organoid model of ovarian endometriosis and the function of estrogen and progesterone in the model

Ruiqi Zhang
Yu’e Yang
Chunfang Ha
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-15
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Single-crystal ZrCo nanoparticle for advanced hydrogen and H-isotope storage

ZrCo, a promising hydrogen isotope storage material, has poor cyclic storage capacity. Here author reveal a defect-derived disproportionation mechanism and report a nano-single-crystal strategy to comprehensively improve performances.

Zhenyang Li
Shiyuan Liu
Jianglan Shui
ResearchOpen Access02 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Single-crystal two-dimensional material epitaxy on tailored non-single-crystal substrates

The heteroepitaxial growth of crystalline 2D materials is usually based on single-crystal substrates. Here, the authors demonstrate that single-crystal graphene and hexagonal boron nitride films can be successfully grown on wafer-scale copper foils with tailored twin boundaries.

Xin Li
Guilin Wu
Wenxin Tang
ResearchOpen Access01 Apr 2022
Nature Communications

Volume: 13, P: 1-8
Integrating bulk and single cell sequencing data to identify prognostic biomarkers and drug candidates in HBV associated hepatocellular carcinoma

Yanjie Zhong
Antony Stalin
Haijie Hu
ResearchOpen Access18 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
A fabrication process for flexible single-crystal perovskite devices

A solution-based lithography-assisted epitaxial-growth-and-transfer method is used to fabricate single-crystal hybrid perovskites on any surface, with precise control of the thickness, area and chemical composition gradient.

Yusheng Lei
Yimu Chen
Sheng Xu
Research29 Jul 2020
Nature

Volume: 583, P: 790-795
Ultrasensitive barocaloric material for room-temperature solid-state refrigeration

A small driving pressure is desirable for practical application of barocaloric materials. Here, the authors demonstrate a sensitive barocaloric effect in NH₄I due to strong reorientation-vibration coupling.

Qingyong Ren
Ji Qi
Bing Li
ResearchOpen Access28 Apr 2022
Nature Communications

Volume: 13, P: 1-9
Improved double DQN with deep reinforcement learning for UAV indoor autonomous obstacle avoidance

Ruiqi Yu
Qingdang Li
Zhen Sun
ResearchOpen Access01 Aug 2025
Scientific Reports

Volume: 15, P: 1-17
SIRT5 inhibition impairs mitochondrial metabolism and enhances venetoclax-induced elimination of acute myeloid leukemia cells

Moran Wang
Ruiqi Zhu
Yu Hu
ResearchOpen Access30 Jun 2025
Leukemia

Volume: 39, P: 1871-1882
Direct conversion of CO and H₂O to hydrocarbons at atmospheric pressure using a TiO₂₋_x/Ni photothermal catalyst

Light-driven synthesis of hydrocarbons could be an attractive route to fuels, but approaches towards this have typically needed H₂ as a reactant. Here the authors report that a TiO₂₋_x/Ni catalyst can produce hydrocarbons from CO and water at atmospheric pressure in a light-driven process.

Xuetao Qin
Ming Xu
Ding Ma
Research05 Jan 2024
Nature Energy

Volume: 9, P: 154-162
Reference values for trans-laminar cribrosa pressure difference and its association with systemic biometric factors

Ruiqi Pang
Danting Lin
Ningli Wang
Research08 Dec 2022
Eye

Volume: 37, P: 2240-2245
A pan-cancer analysis of the role of hexokinase II (HK2) in human tumors

Ruiqi Li
Shuchong Mei
Fuming Zi
ResearchOpen Access05 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
FTIR study on the phase transition of experimental and archaeological burnt ivory

Kai Wang
Yuhang He
Yihang Zhou
ResearchOpen Access22 Aug 2022
Heritage Science

Volume: 10, P: 1-8
Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ear balance organs

Loss of inner ear hair cells leads to permanent hearing loss and balance dysfunction. Whether human utricular cells regenerate is unknown. Here, the authors present a single-cell resource of utricular cells from organ donors and schwannoma patients and describe transcriptional changes during homeostasis and in response to damage.

Tian Wang
Angela H. Ling
Alan G. Cheng
ResearchOpen Access06 Jun 2024
Nature Communications

Volume: 15, P: 1-19
Perovskite superlattices with efficient carrier dynamics

Fabrication of a low-dimensional metal halide perovskite superlattice by chemical epitaxy is reported, with a criss-cross two-dimensional network parallel to the substrate, leading to efficient carrier transport in three dimensions.

Yusheng Lei
Yuheng Li
Sheng Xu
Research10 Aug 2022
Nature

Volume: 608, P: 317-323
Self-healing unmanned aerial vehicle skin for icing prevention and intelligent monitoring

Sijia Xu
Ruiqi Li
Lei Zhang
ResearchOpen Access04 Jul 2025
npj Flexible Electronics

Volume: 9, P: 1-9
GC vitamin D-binding protein gene functional genetic variants and gestational diabetes mellitus risk and prediction

Ruiqi Li
Zhihua Wang
Xiangyuan Yu
ResearchOpen Access30 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
Clinical Features of Congenital and Developmental Cataract in East China: A Five-year Retrospective Review

Xiangjia Zhu
Yu Du
Yi Lu
ResearchOpen Access26 Jun 2017
Scientific Reports

Volume: 7, P: 1-5
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels

Mutations in the cation channel PKD2 cause human autosomal dominant polycystic kidney disease but its channel function and gating mechanism are poorly understood. Here authors study PKD2 using electrophysiology and cryo-EM, which identifies hydrophobic gates and proposes a gating mechanism for PKD2.

Wang Zheng
Xiaoyong Yang
Xing-Zhen Chen
ResearchOpen Access13 Jun 2018
Nature Communications

Volume: 9, P: 1-14
Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout

Tanya J. Major
Riku Takei
Tony R. Merriman
Amendments and Corrections05 Nov 2024
Nature Genetics

Volume: 56, P: 2577
The identification between cognition and reality: the mountain geography of Nanjing in the Southern Song Dynasty (1127–1279) in China

Wenzheng Zhang
Zexin Lei
Yike Hu
ResearchOpen Access24 Jul 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-17
Long-term survival and failure patterns in inoperable early-stage non-small cell lung cancer following stereotactic body radiotherapy: a single-institution retrospective study

Lin Wang
Ruiqi Wang
Yujin Xu
ResearchOpen Access03 Dec 2024
Scientific Reports

Volume: 14, P: 1-10
PI-RADS^AI: introducing a new human-in-the-loop AI model for prostate cancer diagnosis based on MRI

Ruiqi Yu
Ke-wen Jiang
Yu-Dong Zhang
Research04 Jan 2023
British Journal of Cancer

Volume: 128, P: 1019-1029
Comprehensive exploration of programmed cell death landscape in lung adenocarcinoma combining multi-omic analysis and experimental verification

Peng Yu
Leyang Xiao
Wuming Wang
ResearchOpen Access13 Feb 2025
Scientific Reports

Volume: 15, P: 1-18
Single-cell multiomics reveals simvastatin inhibits pan-cancer epithelial-mesenchymal transition via the MEK/ERK pathway in XBP1+ mast cells

Sen Lin
Huimin Zhang
Weijun Luo
ResearchOpen Access28 Nov 2024
Scientific Reports

Volume: 14, P: 1-17
Fabrication of poly(butylene adipate-co-terephthalate) monoliths by thermally induced phase separation and the effect of the annealing process on mechanical properties

In this work, porous PBAT monoliths were fabricated via a solvent-based thermally induced phase separation (TIPS) method, and the pore morphology was tuned by adjusting the solvent ratio and polymer concentration. Furthermore, annealing treatment significantly enhanced the elasticity of the PBAT monoliths, reducing plastic deformation after 70% compression from 43 to 12%. Mechanistic analysis revealed that annealing improved defective crystals formed during phase separation, leading to enhanced structural integrity and mechanical performance.In this work, porous PBAT monoliths were fabricated via a solvent-based thermally induced phase separation (TIPS) method, and the pore morphology was tuned by adjusting the solvent ratio and polymer concentration. Furthermore, annealing treatment significantly enhanced the elasticity of the PBAT monoliths, reducing plastic deformation after 70% compression from 43% to 12%. Mechanistic analysis revealed that annealing improved defective crystals formed during phase separation, leading to enhanced structural integrity and mechanical performance.

Ruiqi Zhang
Yu-I Hsu
Hiroshi Uyama
Research11 Nov 2025
Polymer Journal

Volume: 58, P: 149-158
Global trends in testicular and prostate cancer among adolescents and young adult males aged 15–49 years, 1990–2021: insights from the GBD study

Xinyu Zhang
Yijia Li
Lisheng Peng
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Overcoming the water oxidative limit for ultra-high-workfunction hole-doped polymers

Realizing ultra-high work functions (UHWFs) in hole-doped polymer semiconductors remains a challenge due to water-oxidation reactions. Here, the authors determine the role of water-anion complexes in limiting the work function and develop a design strategy for realizing UHWF polymers.

Qi-Mian Koh
Cindy Guanyu Tang
Peter K. H. Ho
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-10
A novel lipophilic amiloride derivative efficiently kills chemoresistant breast cancer cells

Michelle Hu
Ruiwu Liu
Kermit L. Carraway III
ResearchOpen Access31 Aug 2024
Scientific Reports

Volume: 14, P: 1-13
Inhibition of NOTCH4 sensitizes FLT3/ITD acute myeloid leukemia cells to FLT3 tyrosine kinase inhibition

Ruiqi Zhu
Courtney M. Shirley
Donald Small
Research29 May 2024
Leukemia

Volume: 38, P: 1581-1591
Cullin 4B-RING E3 ligase negatively regulates the immunosuppressive capacity of mesenchymal stem cells by suppressing iNOS

Ruiqi Yu
Hong Han
Gongping Sun
Research14 Aug 2024
Cell Death & Differentiation

Volume: 32, P: 149-161
Mutations of folC cause increased susceptibility to sulfamethoxazole in Mycobacterium tuberculosis

Ruiqi Wang
Kun Li
Yaokai Chen
ResearchOpen Access14 Jan 2021
Scientific Reports

Volume: 11, P: 1-11
Lin28a maintains a subset of adult muscle stem cells in an embryonic-like state

Peng Wang
Xupeng Liu
Ng Shyh-Chang
Research15 May 2023
Cell Research

Volume: 33, P: 712-726
EA-GAN: restoration of text in ancient Chinese books based on an example attention generative adversarial network

Zheng Wenjun
Su Benpeng
Chen Shanxiong
ResearchOpen Access01 Mar 2023
Heritage Science

Volume: 11, P: 1-13
The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease

Yongli Song
Christian F. Guerrero-Juarez
Zhengquan Yu
Research26 May 2020
Cell Research

Volume: 30, P: 854-872
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra
Rainer Malik
Stephanie Debette
Amendments and CorrectionsOpen Access14 Nov 2022
Nature

Volume: 612, P: E7
Functional genetic variants and susceptibility and prediction of gestational diabetes mellitus

Gongchen Huang
Yan Sun
Xiangyuan Yu
ResearchOpen Access05 Aug 2024
Scientific Reports

Volume: 14, P: 1-12

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