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Showing 1–2 of 2 results
Advanced filters: Author: Ruth M. Saecker Clear advanced filters
  • Time-resolved cryo-EM captured transient intermediates during E. coli RNAP promoter melting, revealing conformational changes affecting stepwise transcription bubble opening. Results inform how DNA sequence controls bacterial transcription initiation.

    • Ruth M. Saecker
    • Andreas U. Mueller
    • Seth A. Darst
    Research
    Nature Structural & Molecular Biology
    Volume: 31, P: 1778-1788
  • A spraying-mixing approach for preparing cryo-EM grids using the Spotiton robot allows time-resolved observations of short-lived biomolecular states.

    • Venkata P. Dandey
    • William C. Budell
    • Bridget Carragher
    Research
    Nature Methods
    Volume: 17, P: 897-900