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Advanced filters: Author: Ryan A. Eckerty Clear advanced filters

  • DNA recognition and cleavage control in type II topoisomerases are poorly understood processes. Here, the authors determine cleaved and uncleaved structures of supercoiled DNA-bound topoisomerase VI that reveal how the enzyme activates its cleavage state and prefers to act at deformable substrates.

    • Daniel E. Richman
    • Timothy J. Wendorff
    • James M. Berger
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-15