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Showing 1–10 of 10 results
Advanced filters: Author: Ryan A. Venturelli Clear advanced filters
  • Microbiomes designed with predictable functions could enable broad applications in health, agriculture and bioprocessing. Here the authors use a model-guided approach to design diverse synthetic human gut communities for production of the health-relevant metabolite butyrate.

    • Ryan L. Clark
    • Bryce M. Connors
    • Ophelia S. Venturelli
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16
  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477
  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103
  • Far from frozen and sterile environments, glaciers are biogeochemical reactors and regulators. This Review outlines key biogeochemical and associated physical processes occurring in glacierized environments and the known impacts of glaciers on elemental cycling and the Earth system.

    • Jon. R. Hawkings
    • James A. Bradley
    • Maya P. Bhatia
    Reviews
    Nature Reviews Earth & Environment
    Volume: 7, P: 124-143
  • A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

    • Erola Pairo-Castineira
    • Sara Clohisey
    • J. Kenneth Baillie
    Research
    Nature
    Volume: 591, P: 92-98
  • Using a gate decomposition strategy that requires the calibration of a single pulse, a family of XY entangling gates can be implemented in a superconducting qubit architecture and used to reduce circuit depth for generic quantum algorithms.

    • Deanna M. Abrams
    • Nicolas Didier
    • Colm A. Ryan
    Research
    Nature Electronics
    Volume: 3, P: 744-750
  • Finding the ground state of a variety of complex systems can be formulated as the minimization of the total interaction energy of Ising machines, posing a challenge as computational cost increases exponentially with system size. In this paper, the authors propose an algorithm to find the ground states of Ising-type problems by destabilising non-trivial attractors in combinatorial optimisation solvers through a heuristic modulation of the target amplitude, and show that this provides an improved scaling with respect to several existing methods.

    • Timothée Leleu
    • Farad Khoyratee
    • Kazuyuki Aihara
    ResearchOpen Access
    Communications Physics
    Volume: 4, P: 1-10