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An immunodominant NP_105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Peng et al. find that immunodominant cytotoxic T lymphocytes (CTLs) specific for NP_105–113-B*07:02 are associated with reduced COVID-19 severity. Mechanistically, NP_105–113-B*07:02-specific CTLs show potent antiviral functionality and may represent rational T cell vaccine targets.

Yanchun Peng
Suet Ling Felce
Tao Dong
ResearchOpen Access01 Dec 2021
Nature Immunology

Volume: 23, P: 50-61
Enhanced sensitivity of the LIGO gravitational wave detector by using squeezed states of light

Squeezed states of light have been experimentally demonstrated to improve the performance of the Laser Interferometer Gravitational-wave Observatory (LIGO) in astrophysically relevant frequency regions. This enhanced performance may help to reach the sensitivity required for detecting gravitational waves.

J. Aasi
J. Abadie
J. Zweizig
Research21 Jul 2013
Nature Photonics

Volume: 7, P: 613-619
Defining human ERAD networks through an integrative mapping strategy

Improperly folded proteins are targeted for destruction through the endoplasmic-reticulum-associated degradation pathway (ERAD). Kopito and colleagues present a high-resolution interaction analysis of the ERAD system in combination with functional genomics, and identify new ERAD components.

John C. Christianson
James A. Olzmann
Ron R. Kopito
Research27 Nov 2011
Nature Cell Biology

Volume: 14, P: 93-105
A gravitational wave observatory operating beyond the quantum shot-noise limit

‘Squeezed light’ enables quantum noise in one aspect of light to be reduced by increasing the noise, or more accurately the quantum uncertainty, of a complementary aspect. This has now been used to push the detectors at the heart of the GEO600 gravitational wave observatory to unprecedented levels of sensitivity.

J. Abadie
B. P. Abbott
J. Zweizig
Research11 Sept 2011
Nature Physics

Volume: 7, P: 962-965
The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability

Katie N. Myers
Giancarlo Barone
Spencer J. Collis
ResearchOpen Access14 Oct 2016
Scientific Reports

Volume: 6, P: 1-12
Predicting anterior cruciate ligament failure load with T₂* relaxometry and machine learning as a prospective imaging biomarker for revision surgery

Sean W. Flannery
Jillian E. Beveridge
Braden C. Fleming
ResearchOpen Access02 Mar 2023
Scientific Reports

Volume: 13, P: 1-10

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An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Enhanced sensitivity of the LIGO gravitational wave detector by using squeezed states of light

Defining human ERAD networks through an integrative mapping strategy

A gravitational wave observatory operating beyond the quantum shot-noise limit

The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability

Predicting anterior cruciate ligament failure load with T2* relaxometry and machine learning as a prospective imaging biomarker for revision surgery

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An immunodominant NP_105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Predicting anterior cruciate ligament failure load with T₂* relaxometry and machine learning as a prospective imaging biomarker for revision surgery