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Showing 1–4 of 4 results
Advanced filters: Author: Rylan S. Larsen Clear advanced filters

  • Larsen et al. find that presynaptic NMDA receptors at neocortical synapses are heteromeric receptors containing the developmentally expressed NR3A subunit. Their data also indicate that NR3A-containing presynaptic NMDARs mediate tonic presynaptic activity, synaptic transmission and spike timing–dependent plasticity.

    • Rylan S Larsen
    • Rebekah J Corlew
    • Benjamin D Philpot
    Research
    Nature Neuroscience
    Volume: 14, P: 338-344

  • Catecholaminergic neurons of the ventrolateral medulla are known to drive diverse glucose counterregulatory responses to hypoglycemia. Here, the authors show that projections from these neurons onto nucleus accumbens-targeting neurons of the midline thalamus selectively mediate hypoglycemic feeding.

    • B. Sofia Beas
    • Xinglong Gu
    • Mario A. Penzo
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Spinal cord injury can induce synaptic reorganization and remodeling in the brain. Here the authors study how severed distal axons signal back to the cell body to induce hyperexcitability, loss of inhibition and enhanced presynaptic release through netrin-1.

    • Tharkika Nagendran
    • Rylan S. Larsen
    • Anne Marion Taylor
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16

  • NMDA receptors that contain GluN3 subunits have several non-conventional properties that set them apart from 'classical' NMDA receptors. Pérez-Otaño and colleagues describe the important roles of these receptors in CNS development and their potential involvement in CNS disease.

    • Isabel Pérez-Otaño
    • Rylan S. Larsen
    • John F. Wesseling
    Reviews
    Nature Reviews Neuroscience
    Volume: 17, P: 623-635