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The induction of apoptosis in HeLa cells by the loss of LBP-p40

Yasufumi Kaneda
Yoshinao Kaneda
Kiyoji Tanaka
Research28 Jan 1998
Cell Death & Differentiation

Volume: 5, P: 20-28
Sex difference in BAT thermogenesis depends on PGC-1α–mediated phospholipid synthesis in mice

Brown adipose tissue (BAT) plays a role in energy expenditure but its thermogenic activities differ between sexes. Here, the authors show that PGC-1α enhances mitochondrial function and BAT thermogenesis in females by promoting phospholipid synthesis and enhancing estrogen signaling.

Akira Takeuchi
Kazutaka Tsujimoto
Tetsuya Yamada
ResearchOpen Access14 Jul 2025
Nature Communications

Volume: 16, P: 1-16
Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis

Besides hepatocytes, resident immune cells of the liver are also contributing to the body’s energy homeostasis. Here authors show that group 2 innate lymphoid cells interact with a specific set of hepatocytes in suppressing gluconeogenesis and regulate blood glucose levels via Interleukin-13 signalling.

Masanori Fujimoto
Masataka Yokoyama
Tomoaki Tanaka
ResearchOpen Access15 Sept 2022
Nature Communications

Volume: 13, P: 1-21
Car4-positive adipocyte progenitor cells adapt to the aging environment and work as protection against ROS via glutathione metabolism

Masato Horino
Kenji Ikeda
Tetsuya Yamada
ResearchOpen Access29 Aug 2025
Scientific Reports

Volume: 15, P: 1-15
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

In vitro studies in human cell lines and in vivo studies in a hamster model show that the SARS-CoV-2 Omicron variant is less pathogenic than both the Delta variant and an ancestral strain of SARS-CoV-2.

Rigel Suzuki
Daichi Yamasoba
Kei Sato
ResearchOpen Access01 Feb 2022
Nature

Volume: 603, P: 700-705
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Allele-specific inactivation of the α4 integrin gene expression in fibrosarcoma cell lines and relevance for spontaneous metastasis

Shuichi Sato
Katsumasa Tunashima
Ryo Kominami
Research14 Jul 1998
Oncogene

Volume: 17, P: 105-113
Strawberry notch 1 safeguards neuronal genome via regulation of Yeats4 expression

Dai Ihara
Ayano Narumoto
Yu Katsuyama
ResearchOpen Access24 Jul 2025
Cell Death Discovery

Volume: 11, P: 1-11
Machine learning-based high-benefit approach versus traditional high-risk approach in statin therapy: the Shizuoka Kokuho database study

Ryo Watanabe
Eiji Nakatani
Akira Sugawara
ResearchOpen Access29 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Increased fat accumulation may be associated with severe muscle wasting in critically ill patients: a prospective observational study

Yasutaka Koga
Motoki Fujita
Ryosuke Tsuruta
ResearchOpen Access03 Apr 2025
Scientific Reports

Volume: 15, P: 1-9
Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα⁺ mesenchymal cells from bone marrow

Eriko Aikawa
Ryo Fujita
Katsuto Tamai
ResearchOpen Access05 Jun 2015
Scientific Reports

Volume: 5, P: 1-13
EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma

Yuko Kusakabe
Tetsuhiro Chiba
Naoya Kato
ResearchOpen Access01 Nov 2021
Scientific Reports

Volume: 11, P: 1-14
Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats

Haruka Wada
Yuhei Shibata
Ken-ichiro Seino
ResearchOpen Access29 Nov 2019
Scientific Reports

Volume: 9, P: 1-12

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The induction of apoptosis in HeLa cells by the loss of LBP-p40

Sex difference in BAT thermogenesis depends on PGC-1α–mediated phospholipid synthesis in mice

Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis

Car4-positive adipocyte progenitor cells adapt to the aging environment and work as protection against ROS via glutathione metabolism

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Allele-specific inactivation of the α4 integrin gene expression in fibrosarcoma cell lines and relevance for spontaneous metastasis

Strawberry notch 1 safeguards neuronal genome via regulation of Yeats4 expression

Machine learning-based high-benefit approach versus traditional high-risk approach in statin therapy: the Shizuoka Kokuho database study

Increased fat accumulation may be associated with severe muscle wasting in critically ill patients: a prospective observational study

Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα⁺ mesenchymal cells from bone marrow

EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma

Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats

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