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Showing 1–6 of 6 results
Advanced filters: Author: Ryoji Suno Clear advanced filters

  • Structural analysis of prostaglandin E receptor EP3, a member of the prostanoid receptor subfamily of GPCRs, in complex with the endogenous agonist PGE2 reveals important interactions and motions required for receptor activation.

    • Kazushi Morimoto
    • Ryoji Suno
    • Takuya Kobayashi
    Research
    Nature Chemical Biology
    Volume: 15, P: 8-10

  • A cryo-EM structure of the active human melatonin receptor in complex with Gi reveals conformational changes upon activation and the molecular basis for G-protein selectivity.

    • Hiroyuki H. Okamoto
    • Hirotake Miyauchi
    • Osamu Nureki
    Research
    Nature Structural & Molecular Biology
    Volume: 28, P: 694-701

  • Katayama et al. report a vibrational spectroscopic study using ATR–FTIR of the human M2 muscarinic acetylcholine receptor (M2R). Their work involves an extensive comparison of agonists, antagonists, and inverse agonists, in which they show that they C = O stretching amide–I band is correlated with the ligand binding efficiency.

    • Kota Katayama
    • Kohei Suzuki
    • Hideki Kandori
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12