We showed that various i-motif-forming DNAs undergo LLPS with cationic peptide in acidic conditions. Considering cellular condition, we further investigated LLPS of DNAs in the molecular crowding conditions at physiological pH. LLPS is promoted by molecular crowding conditions at even in basic pH through stabilization of i-motif structure by molecular crowding condition.
- Ryosuke Suzuki
- Mitsuki Tsuruta
- Daisuke Miyoshi
