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Showing 1–14 of 14 results
Advanced filters: Author: Sébastien Merkel Clear advanced filters

  • This case study discusses two patients with locally advanced Merkel cell carcinoma. The authors describe how neoadjuvant polychemotherapy was used to treat these patients allowing curative-intent surgery plus radiotherapy.

    • Thomas Jouary
    • Nathalie Lalanne
    • Alain Taieb
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 6, P: 544-548

  • The way in which seismic waves pass through the core suggests alignment of iron crystals within the solid inner core. Experiments indicate that iron at inner-core conditions may be weaker than thought and easily allow deformation of iron crystals.

    • Sébastien Merkel
    News & Views
    Nature Geoscience
    Volume: 6, P: 514-515

  • For archival pathogens, like pH1N1 Influenza A virus the causative agent of 1918/19 pandemic, only few whole genome sequences exist. Here, Patrono et al. provide one complete and two partial genomes from Germany and find variation in two sites in the nucleoprotein gene in pandemic samples compared to pre-pandemic samples, that are associated with resistance to host antiviral response, pointing at a possible viral adaptation to humans.

    • Livia V. Patrono
    • Bram Vrancken
    • Sébastien Calvignac-Spencer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • Combining laser-driven shock compression and ultra-short X-ray pulses from LCLS, the local structure of liquid silicates was determined up to 385 GPa. Compared with molecular dynamics calculations, continuous densification of O-O and Mg-Si networks may alter melt properties and impact planetary differentiation.

    • Guillaume Morard
    • Jean-Alexis Hernandez
    • Alessandra Ravasio
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9

  • The D\({}^{{\prime\prime} }\) layer in the Earth’s lower mantle involves a seismic discontinuity which is often assigned to a mineral phase transition to post-perovskite, however, as this phase transition occurs over broad region the assignment of seismic boundaries remains unclear. Here, the authors find that due to the kinetics of the bridgmanite to post-perovskite transformation, thick transition layers can be detected by seismic reflections, unlike previously thought.

    • Christopher Langrand
    • Denis Andrault
    • Sébastien Merkel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-9

  • A species-level phylogenetic analysis of the high-elevation flora of the European Alps reveals that the flora is young and colonist rich. Its assembly was primarily driven by the Pleistocene climatic cycles, rather than ancient orogenic events.

    • Lara M. Wootton
    • Florian C. Boucher
    • Sébastien Lavergne
    Research
    Nature Plants
    Volume: 11, P: 1142-1153

  • There are competing hypotheses for human herpes simplex virus 2’s migration out-of-Africa. Here, the authors sequence 65 new herpes simplex virus 2 genomes with a focus on under-sampled sub-Saharan African countries, suggesting an Eastern African origin for global dispersal the virus between 22-29 thousand years ago.

    • Jennifer L. Havens
    • Sébastien Calvignac-Spencer
    • Joel O. Wertheim
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Here, the authors use full-plastome phylogenomics and multiclade comparative models to reconstruct the tempo and drivers of six European Alpine angiosperm lineages before and during the Pleistocene. They find that geographic divergence and bedrock shifts drive speciation events, while diversification rates remained steady.

    • Jan Smyčka
    • Cristina Roquet
    • Sébastien Lavergne
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • What happens to minerals under the conditions characteristic of the Earth at great depths? Experiments performed under such conditions illustrate how the main constituent of the lower mantle may behave.

    • Sébastien Merkel
    News & Views
    Nature
    Volume: 428, P: 812-813

  • An anthrax-causing agent, Bacillus cereus biovar anthracis, is a persistent and widespread cause of death for a broad range of mammalian hosts in a tropical rainforest, with important implications for the conservation of mammals such as chimpanzees.

    • Constanze Hoffmann
    • Fee Zimmermann
    • Fabian H. Leendertz
    Research
    Nature
    Volume: 548, P: 82-86