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British Journal of Cancer (39)
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Showing 1–50 of 106 results

Advanced filters: Author: S Anttila Clear advanced filters

Mapping the genetic landscape across 14 psychiatric disorders

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Andrew D. Grotzinger
Josefin Werme
Jordan W. Smoller
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 406-415
Atlantic salmon show capability for cardiac acclimation to warm temperatures

Cardiac function can limit high-temperature tolerance in fish. Here, Antilla et al.show similar cardiac responses to warming for two wild Atlantic salmon populations with different environmental temperatures, which suggests that cardiac plasticity is independent of natural habitat.

Katja Anttila
Christine S. Couturier
Anthony P. Farrell
Research24 Jun 2014
Nature Communications

Volume: 5, P: 1-6
Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila and colleagues report meta-analysis of 29 genome-wide association studies for migraine. They identify five loci newly associated with migraine, three of which are associated with specific subtypes of migraine with or without aura.

Verneri Anttila
Bendik S Winsvold
Aarno Palotie
Research23 Jun 2013
Nature Genetics

Volume: 45, P: 912-917
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Aarno Palotie and colleagues present results of a large genome-wide association study of migraine. They identified significant associations at 38 distinct loci and found enrichment for genes expressed in vascular and smooth muscle tissues.

Padhraig Gormley
Verneri Anttila
Aarno Palotie
Research20 Jun 2016
Nature Genetics

Volume: 48, P: 856-866
Expression of transcription factor AP-2α predicts survival in epithelial ovarian cancer

M A Anttila
J K Kellokoski
V-M Kosma
ResearchOpen Access23 May 2000
British Journal of Cancer

Volume: 82, P: 1974-1983
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

Arno Palotie, Verneri Anttila and colleagues report a genome-wide association study of migraine. They identify a variant on chromosome 8q22.1 associated with risk of migraine.

Verneri Anttila
Hreinn Stefansson
Aarno Palotie
Research29 Aug 2010
Nature Genetics

Volume: 42, P: 869-873
Insulin-like Growth Factor I and Insulin-like Growth Factor Binding Protein 3 as Determinants of Blood Hemoglobin Concentration in Healthy Subjects

Raija Anttila
Riitta Koistinen
Martti A Siimes
Research01 Dec 1994
Pediatric Research

Volume: 36, P: 745-748
Endogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicity

K Kinnula
K Linnainmaa
VL Kinnula
Research01 Apr 1998
British Journal of Cancer

Volume: 77, P: 1097-1102
CanScreen5, a global repository for breast, cervical and colorectal cancer screening programs

In the first results from an ongoing global cancer screening data repository, screening program organization was better overall in Europe compared to other continents; however, there were substantial gaps in implementation across both high- and low-resource settings.

Li Zhang
Isabel Mosquera
Melanie Ann Layne
ResearchOpen Access27 Apr 2023
Nature Medicine

Volume: 29, P: 1135-1145
p21/WAF1 expression as related to p53, cell proliferation and prognosis in epithelial ovarian cancer

M A Anttila
V-M Kosma
K Syrjänen
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1870-1878
Skin cancer screening participation and impact on melanoma incidence in Germany – an observational study on incidence trends in regions with and without population-based screening

A Waldmann
S Nolte
A Katalinic
ResearchOpen Access31 Jan 2012
British Journal of Cancer

Volume: 106, P: 970-974
Overdiagnosis due to breast cancer screening: updated estimates of the Helsinki service study in Finland

S Heinävaara
T Sarkeala
A Anttila
ResearchOpen Access14 Aug 2014
British Journal of Cancer

Volume: 111, P: 1463-1468
Cascading impacts of climate change on child survival and health in Africa

Children will bear considerable burdens of climate change, particularly where impacts intersect with pre-existing vulnerabilities. In this Perspective, the authors highlight how climate factors and socio-political stratifiers increase children’s risks in Africa and propose action to break vulnerability cycles.

Loan Diep
Samuel Godfrey
Priti Parikh
Reviews04 Mar 2025
Nature Climate Change

Volume: 15, P: 254-261
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

The oncoprotein c-Myc is often overexpressed in triple negative breast cancer and has a role in tumor progression and resistance to therapy. Here the authors show that elevated MYC expression is correlated with low immune infiltration, diminished MHC-I pathway expression and that CpG/aOX40 treatment could overcome resistance to PD-L1 blockade in MYC-high breast tumors.

Joyce V. Lee
Filomena Housley
Andrei Goga
ResearchOpen Access27 Jun 2022
Nature Communications

Volume: 13, P: 1-12
Phase II trial of UFT in advanced colorectal and gastric cancer

STA Malik
D Talbot
ML Slevin
Research01 Dec 1990
British Journal of Cancer

Volume: 62, P: 1023-1025
ENSO impacts child undernutrition in the global tropics

The El Nino Southern Oscillation (ENSO) influences the weather around the world and, therefore, has strong impacts on society. Here, the authors show that ENSO is associated with child nutrition in many countries, with warmer El Niño conditions leading to more child undernutrition in large parts of the developing world.

Jesse K. Anttila-Hughes
Amir S. Jina
Gordon C. McCord
ResearchOpen Access12 Oct 2021
Nature Communications

Volume: 12, P: 1-8
50 years of screening in the Nordic countries: quantifying the effects on cervical cancer incidence

S Vaccarella
S Franceschi
F Bray
ResearchOpen Access03 Jul 2014
British Journal of Cancer

Volume: 111, P: 965-969
Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

The tumour microenvironment has not been fully characterised in high-grade serous ovarian cancers (HGSOC). Here, the authors use highly multiplexed imaging to analyse the HGSOC immune microenvironment at spatial and single-cell resolution, with clinically relevant findings for BRCA1/2-mutated tumours.

I.-M. Launonen
N. Lyytikäinen
A. Färkkilä
ResearchOpen Access11 Feb 2022
Nature Communications

Volume: 13, P: 1-14
Improved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’

Lucie Gerber
Kathy A. Clow
Anthony K. Gamperl
ResearchOpen Access10 Dec 2020
Scientific Reports

Volume: 10, P: 1-12
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

Integration of GWAS and single-cell transcriptomic data from the entire nervous system systematically identifies cell types underlying brain complex traits and provides insights into the etiology of Parkinson’s disease.

Julien Bryois
Nathan G. Skene
Patrick F. Sullivan
Research27 Apr 2020
Nature Genetics

Volume: 52, P: 482-493
Beyond a single pole: exploring the nuanced coexistence of scientific elitism and populism in China

Shuo Wang
Tuo Wang
Zhengfeng Li
ResearchOpen Access10 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-13
11 IS INCREASING SERUM TRANSFERRIN AN INDICATOR OF IRON DEFICIENCY, OR OF ACTIVE ERYTHROPOIESIS IN PUBERTAL BOYS?

Raija Anttila
Martti A Siimes
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 4
Deletions at 14q in malignant mesothelioma detected by microsatellite marker analysis

A-M Björkqvist
M Wolf
S Knuutila
ResearchOpen Access12 Nov 1999
British Journal of Cancer

Volume: 81, P: 1111-1115
Serum Transferrin Receptor for Assessment of Iron Status in Healthy Prepubertal and Early Pubertal Boys

Sanna M Kivivuori
Raija Anttila
Martti A Siimes
Research01 Sept 1993
Pediatric Research

Volume: 34, P: 297-299
Cyclin D1, cyclin E, and p21 have no apparent prognostic value in anal carcinomas treated by radiotherapy with or without chemotherapy

A S Allal
P Gervaz
M-A Bründler
ResearchOpen Access03 Aug 2004
British Journal of Cancer

Volume: 91, P: 1239-1244
Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung

A-M Björkqvist
L Tammilehto
S Knuutila
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 260-269
Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2

M Schuyer
M E L van der Burg
E M J J Berns
ResearchOpen Access30 Oct 2001
British Journal of Cancer

Volume: 85, P: 1359-1367
Cerebral small vessel disease genomics and its implications across the lifespan

White matter hyperintensities (WMH) are a common brain-imaging feature of cerebral small vessel disease. Here, the authors carry out a GWAS and followup analyses for WMH-volume, implicating several variants with potential for risk stratification and drug targeting.

Muralidharan Sargurupremraj
Hideaki Suzuki
Stéphanie Debette
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-18
Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area

S Bulk
O Visser
C J L M Meijer
ResearchOpen Access26 Aug 2003
British Journal of Cancer

Volume: 89, P: 834-839
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.

Yanjun Guo
Pamela M. Rist
Daniel I. Chasman
ResearchOpen Access06 Jul 2020
Nature Communications

Volume: 11, P: 1-11
Integrating common and rare genetic variation in diverse human populations

Here, the analysis of 'HapMap 3' is reported — a public data set of genomic variants in human populations. The resource integrates common and rare single nucleotide polymorphisms (SNPs) and copy number polymorphisms (CNPs) from 11 global populations, providing insights into population-specific differences among variants. It also demonstrates the feasibility of imputing newly discovered rare SNPs and CNPs.

David M. Altshuler
Richard A. Gibbs
Jean E. McEwen
Research02 Sept 2010
Nature

Volume: 467, P: 52-58
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Better analytical methods are needed to extract biological meaning from genome-wide association studies (GWAS) of psychiatric disorders. Here the authors take GWAS data from over 60,000 subjects, including patients with schizophrenia, bipolar disorder and major depression, and identify common etiological pathways shared amongst them.

Colm O'Dushlaine
Lizzy Rossin
Gerome Breen
Research19 Jan 2015
Nature Neuroscience

Volume: 18, P: 199-209
Genome-wide association study reveals three susceptibility loci for common migraine in the general population

Markus Schürks and colleagues report a genome-wide association study for common migraine. They identify three new susceptibility loci at PRDM16, TRPM8 and LRP1.

Daniel I Chasman
Markus Schürks
Tobias Kurth
Research12 Jun 2011
Nature Genetics

Volume: 43, P: 695-698
Complement studies in nephrotoxic serum nephritis (NSN) and aminonucleoside nephrosis (AN) of the rat

H Geiger
R A Good
H Bickel
Research01 Nov 1974
Pediatric Research

Volume: 8, P: 901
Correction: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Padhraig Gormley
Verneri Anttila
Aarno Palotie
Amendments and Corrections28 Sept 2016
Nature Genetics

Volume: 48, P: 1296
Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

Joyce V. Lee
Filomena Housley
Andrei Goga
Amendments and CorrectionsOpen Access21 Nov 2022
Nature Communications

Volume: 13, P: 1-2
Thermal tolerance and vulnerability to warming differ between populations of wild Oncorhynchus mykiss near the species’ southern range limit

T. L. Dressler
V. Han Lee
E. J. Eliason
ResearchOpen Access04 Sept 2023
Scientific Reports

Volume: 13, P: 1-16
9 THE EFFECT OF GASTRIC PH ON THE ABSORPTION OF KETOCONAZOLE BY VERY-LOW-BIRTH-WEIGHT INFANTS

John N Van Den Anker
Ania Van Ussel-Dijk
Pieter J J Sauer
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 4
10 AMOXICILLIN PHARMACOKINETICS IN THE PRETERM INFANT

John N Van Den Anker
Janetta J Huisman-De Boer
Ronald De Groot
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 4
The participatory turn in health and medicine: The rise of the civic and the need to ‘give back’ in data-intensive medical research

Lotje E. Siffels
Tamar Sharon
Andrew S. Hoffman
ResearchOpen Access01 Dec 2021
Humanities and Social Sciences Communications

Volume: 8, P: 1-10
Recurrent DNA copy number changes in 1q, 4q, 6q, 9p, 13q, 14q and 22q detected by comparative genomic hybridization in malignant mesothelioma

A-M Björkqvist
L Tammilehto
S Knuutila
Research01 Feb 1997
British Journal of Cancer

Volume: 75, P: 523-527
Metabolic acidosis in patients receiving anticonvulsants

I Matsuda
B Nagai
M Homma
Research01 Jan 1979
Pediatric Research

Volume: 13, P: 87
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

Elise Robinson, Mark Daly and colleagues present an analysis of genetic data from autism spectrum disorder (ASD) and population-based studies and find evidence for genetic correlations between ASDs and typical variation in social behavior and communication traits. These results may inform genetic models of ASDs and other neuropsychiatric disorders.

Elise B Robinson
Beate St Pourcain
Mark J Daly
Research21 Mar 2016
Nature Genetics

Volume: 48, P: 552-555
Influence of dust and sea-salt sandwich effect on precipitation chemistry over the Western Ghats during summer monsoon

L. Yang
S. Mukherjee
P. D. Safai
ResearchOpen Access16 Dec 2019
Scientific Reports

Volume: 9, P: 1-13
Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer

H Wikman
S Ruosaari
S Anttila
Research12 Feb 2007
Oncogene

Volume: 26, P: 4730-4737
Effectiveness of national cervical cancer screening programme in Taiwan: 12-year experiences

Y-Y Chen
S-L You
C-J Chen
ResearchOpen Access16 Jun 2009
British Journal of Cancer

Volume: 101, P: 174-177
Regulation of Heart Rate Variation by the Autonomic Nervous System in Neonatal Lambs

Anja S I Siimes
Ilkka A T Välimäki
H S Samuli Sarajas
Research01 Apr 1990
Pediatric Research

Volume: 27, P: 383-391
IFITM3 restricts the morbidity and mortality associated with influenza

Interferon-inducible transmembrane (IFITM) protein 3 is shown to be an innate defence mechanism against viral infection in vivo; furthermore, a subset of the patients hospitalized during the H1N1 2009 pandemic carried a variant form of the IFITM3 gene.

Aaron R. Everitt
Simon Clare
Paul Kellam
Research25 Mar 2012
Nature

Volume: 484, P: 519-523
Tumour growth rate and DNA flow cytometry parameters as prognostic factors in metastatic melanoma

T Muhonen
S Pyrhönen
L Kangas
Research01 Sept 1992
British Journal of Cancer

Volume: 66, P: 528-532

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