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Showing 1–5 of 5 results

Advanced filters: Author: S Vangveravong Clear advanced filters

Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer

C Zeng
S Vangveravong
R H Mach
ResearchOpen Access08 Oct 2013
British Journal of Cancer

Volume: 109, P: 2368-2377
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

The sigma-2 receptor is used as a biomarker for tumour cell proliferation but its identity is unknown. Using a novel radiolabelled probe, the authors identify progesterone receptor membrane component 1, which is overexpressed in several tumour types, as the putative sigma-2 receptor.

Jinbin Xu
Chenbo Zeng
Robert H. Mach
Research05 Jul 2011
Nature Communications

Volume: 2, P: 1-7
Cytotoxic sigma-2 ligands trigger cancer cell death via cholesterol-induced-ER-stress

Rony Takchi
Bethany C. Prudner
Dirk Spitzer
ResearchOpen Access02 May 2024
Cell Death & Disease

Volume: 15, P: 1-14
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer

Takaomi Hagi
Suwanna Vangveravong
Dirk Spitzer
ResearchOpen Access16 Mar 2024
Scientific Reports

Volume: 14, P: 1-13
Sigma-2 ligands induce tumour cell death by multiple signalling pathways

C Zeng
J Rothfuss
R H Mach
ResearchOpen Access17 Jan 2012
British Journal of Cancer

Volume: 106, P: 693-701