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Showing 101–150 of 445 results

Advanced filters: Author: S Yoshimura Clear advanced filters

Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection

The synthesis of NPY and its receptor Y1R increases in lung phagocytes during severe influenza virus infection, leading to the induction of SOCS3 and impaired antiviral response and increased pro-inflammatory cytokine production.

Seiki Fujiwara
Midori Hoshizaki
Yumiko Imai
Research19 Nov 2018
Nature Microbiology

Volume: 4, P: 258-268
Copolymerization of N-Arylmaleimide with Vinyl Acetate—Effect of the Total Monomer Concentration on the Reactivity Ratios of the Copolymerization

M Z Elsabee
M W Sabaa
S Mokhtar
Research01 Jun 1985
Polymer Journal

Volume: 17, P: 737-746
Cytokines and interventional immunology

David A. Hafler
Editorial01 Jun 2007
Nature Reviews Immunology

Volume: 7, P: 423
The decline and fate of an iron-induced subarctic phytoplankton bloom

Philip W. Boyd
Cliff S. Law
Takeshi Yoshimura
Research17 Mar 2004
Nature

Volume: 428, P: 549-553
Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

This report by the Consortium for Refractive Error and Myopia uses gene-environment-wide interaction study (GEWIS) to identify genetic loci that affect environmental influence in myopia development, and identifies ethnic specific genetic loci that attribute to eye refractive errors.

Qiao Fan
Virginie J. M. Verhoeven
Kari Matti Mäkelä
ResearchOpen Access06 Apr 2016
Nature Communications

Volume: 7, P: 1-12
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

A study of SARS-CoV-2 variants examining their transmission, infectivity, and potential resistance to therapies provides insights into the biology of the Delta variant and its role in the global pandemic.

Petra Mlcochova
Steven A. Kemp
Ravindra K. Gupta
ResearchOpen Access06 Sept 2021
Nature

Volume: 599, P: 114-119
Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo

Vanessa Cull
Peta A Tilbrook
S Peter Klinken
Research01 Mar 2000
Oncogene

Volume: 19, P: 953-960
Cooling positronium to ultralow velocities with a chirped laser pulse train

The one-dimensional laser cooling of positronium enables testing of quantum electrodynamics and could realize Bose–Einstein condensation in positronium.

K. Shu
Y. Tajima
K. Yoshioka
ResearchOpen Access11 Sept 2024
Nature

Volume: 633, P: 793-797
Dynamic plasticity in phototransduction regulates seasonal changes in color perception

Animal coloration and behavior can change seasonally, but it is unclear if visual sensitivity to color shifts as well. Here, Shimmura et al. show that medaka undergo seasonal behavioral change accompanied by altered expression of opsin genes, resulting in reduced visual sensitivity to mates during winter-like conditions.

Tsuyoshi Shimmura
Tomoya Nakayama
Takashi Yoshimura
ResearchOpen Access04 Sept 2017
Nature Communications

Volume: 8, P: 1-7
Author Correction: Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis

Hitomi Takada
Yohei Sasagawa
Akira Kurisaki
Amendments and CorrectionsOpen Access17 Oct 2023
Nature Communications

Volume: 14, P: 1
A prospective study of stomach cancer death in relation to green tea consumption in Japan

Y Hoshiyama
T Kawaguchi
T Yoshimura
ResearchOpen Access23 Jul 2002
British Journal of Cancer

Volume: 87, P: 309-313
Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

Myopia is a significant and increasing public health concern. Here Miyake et al. conduct a genome-wide association study and identify WNT7Bas a susceptibility gene across different ethnic groups, suggesting a possible role in the development of myopia.

Masahiro Miyake
Kenji Yamashiro
Nagahisa Yoshimura
Research31 Mar 2015
Nature Communications

Volume: 6, P: 1-9
Characterization of the mouse Ron/Stk receptor tyrosine kinase gene

Susan E Waltz
Christy LV Toms
Sandra J Friezner Degen
Research21 Jan 1998
Oncogene

Volume: 16, P: 27-42
Tracing the origin of hair follicle stem cells

Live imaging and single-cell transcriptomics of mouse hair follicles reveal their development from 2D concentric zones in the placode to 3D longitudinal compartments, one of which is a stem cell compartment.

Ritsuko Morita
Noriko Sanzen
Hironobu Fujiwara
Research09 Jun 2021
Nature

Volume: 594, P: 547-552
Vanadium disulfide flakes with nanolayered titanium disulfide coating as cathode materials in lithium-ion batteries

VS₂ is a promising cathode material for lithium-ion batteries, but is susceptible to Peierls distortion during (de)lithiation. Here the authors show that VS₂ cathodes can be stabilized by conformally coating them with a nanoscale TiS₂ protective layer, leading to impressive electrochemical performance.

Lu Li
Zhaodong Li
Nikhil Koratkar
ResearchOpen Access16 Apr 2019
Nature Communications

Volume: 10, P: 1-10
Erratum: Functional annotation of chemical libraries across diverse biological processes

Jeff S Piotrowski
Sheena C Li
Charles Boone
Amendments and Corrections21 Nov 2017
Nature Chemical Biology

Volume: 13, P: 1286
Dynein arms are oscillating force generators

Chikako Shingyoji
Hideo Higuchi
Toshio Yanagida
Research18 Jun 1998
Nature

Volume: 393, P: 711-714
Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase

Cell rounding at mitosis is driven by cortical tension and maintained through metaphase, although the mechanism is unknown. Here, the authors demonstrate that Cdk1 phosphorylation of DIAPH1 is required for both cortical tension maintenance and inactivation of the spindle assembly checkpoint.

Koutarou Nishimura
Yoshikazu Johmura
Makoto Nakanishi
ResearchOpen Access28 Feb 2019
Nature Communications

Volume: 10, P: 1-12
Exploring the effect of alcohol on disease activity and outcomes in rheumatoid arthritis through systematic review and meta-analysis

Jaime N. Turk
Erin R. Zahavi
Douglas J. Veale
ResearchOpen Access18 May 2021
Scientific Reports

Volume: 11, P: 1-6
Differential regulation of SOCS genes in normal and transformed erythroid cells

Mohinder K Sarna
Evan Ingley
Peta A Tilbrook
Research22 May 2003
Oncogene

Volume: 22, P: 3221-3230
Predictive value of heart rate deceleration capacity on coronary artery lesion in acute phase of Kawasaki disease

Yaheng Lu
Yonghong Guo
Xianmin Wang
ResearchOpen Access23 Jun 2020
Scientific Reports

Volume: 10, P: 1-6
A gp130–Src–YAP module links inflammation to epithelial regeneration

This study demonstrates the activation of a STAT3-independent healing pathway in response to mucosal injury which involves the co-receptor for IL-6 cytokines gp130 and downstream effectors Src, Yes, YAP and Notch.

Koji Taniguchi
Li-Wha Wu
Michael Karin
Research25 Feb 2015
Nature

Volume: 519, P: 57-62
Activation of monocytes, T-lymphocytes and plasma inflammatory markers in angina patients

Won-Ha Lee
Yoon Lee
Jeong-Euy Park
ResearchOpen Access01 Sept 1999
Experimental & Molecular Medicine

Volume: 31, P: 159-164
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-mapping analysis of a previously identified disease-associated locus, LOXL1. They identify a rare protective variant in LOXL1 exclusive to the Japanese population and five new common variant susceptibility loci.

Tin Aung
Mineo Ozaki
Chiea Chuen Khor
Research29 May 2017
Nature Genetics

Volume: 49, P: 993-1004
Current-induced magnetic domain wall motion below intrinsic threshold triggered by Walker breakdown

Current-induced magnetic domain wall motion can be triggered by an applied magnetic field, and its motion is described by the vector sum of the velocities imparted by current and magnetic field driving terms.

T. Koyama
K. Ueda
T. Ono
Research09 Sept 2012
Nature Nanotechnology

Volume: 7, P: 635-639
Coherence–incoherence and dimensional crossover in layered strongly correlated metals

T. Valla
P. D. Johnson
T. Sasaki
Research06 Jun 2002
Nature

Volume: 417, P: 627-630
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

The spike protein of the Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 than Delta, and a marked change in its antigenicity increases Omicron’s evasion of therapeutic and vaccine-elicited neutralizing antibodies.

Bo Meng
Adam Abdullahi
Ravindra K. Gupta
ResearchOpen Access01 Feb 2022
Nature

Volume: 603, P: 706-714
The inflationary Universe—birth, death and transfiguration

John D. Barrow
Michael S. Turner
Reviews26 Aug 1982
Nature

Volume: 298, P: 801-805
Monitoring Neonatal Peripheral Circulation by Electrocardiogram-to-Oximeter Pulse Velocity

Masaya Oishi
Hiroshi Nishida
Jun Hoshi
Research01 Jun 1993
Pediatric Research

Volume: 33, P: 653-657
Intravenous L-Carnitine and Acetyl-L-Carnitine in Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency and Isovaleric Acidemia

J L K Van Hove
S G Kahler
C R Roe
Research01 Jan 1994
Pediatric Research

Volume: 35, P: 96-101
Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case–control study

Andrew J Walley
Christophe Aucan
Adrian V S Hill
Research03 Dec 2003
European Journal of Human Genetics

Volume: 12, P: 132-138
A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy

Zhenglin Yang and colleagues use whole-exome sequencing to identify a rare variant in the FGD6 gene that is associated with the polypoidal choroidal vasculopathy subtype of wet age-related macular degeneration. They show that FGD6 regulates proangiogenic effects together with VEGF and that the mutation results in abnormal retinal vessel development.

Lulin Huang
Houbin Zhang
Zhenglin Yang
Research18 Apr 2016
Nature Genetics

Volume: 48, P: 640-647
CLP1 links tRNA metabolism to progressive motor-neuron loss

Inactivating the CLP1 RNA kinase in mice leads to a progressive loss of motor neurons, through a mechanism related to the accumulation of a novel set of small RNA fragments derived from aberrant processing of tyrosine pre-transfer RNA.

Toshikatsu Hanada
Stefan Weitzer
Josef M. Penninger
Research10 Mar 2013
Nature

Volume: 495, P: 474-480
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system

Jason S Stumhofer
Arian Laurence
Christopher A Hunter
Research13 Aug 2006
Nature Immunology

Volume: 7, P: 937-945
Carnitine during Prolonged Breast Feeding

Liisa M Rovamo
Leena Salmenperä
Kari O Raivio
Research01 Aug 1986
Pediatric Research

Volume: 20, P: 806-809
SOCS-3 regulates onset and maintenance of T_H2-mediated allergic responses

Yoh-ichi Seki
Hiromasa Inoue
Masato Kubo
Research29 Jun 2003
Nature Medicine

Volume: 9, P: 1047-1054
The Influence of Pulsatile Perfusion on the Vascular Properties of the Newborn Lamb Lung

E H Johnson
S H Bennett
B W Goetzman
Research01 Apr 1992
Pediatric Research

Volume: 31, P: 349-353
T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

Kohei Ota
Makoto Matsui
David A. Hafler
Research12 Jul 1990
Nature

Volume: 346, P: 183-187
Globally coherent water cycle response to temperature change during the past two millennia

Global temperature fluctuations during the last 2,000 years caused consistent changes in ocean evaporation and atmospheric moisture condensation processes, reflected in coherent water isotope signals in a large compilation of proxy records.

Bronwen L. Konecky
Nicholas P. McKay
Kei Yoshimura
Research02 Nov 2023
Nature Geoscience

Volume: 16, P: 997-1004
Anti-tumour activity of low-toxicity lipopolysaccharide of Bordetella pertussis

M Ohnishi
S Kimura
H Yamaguchi
Research01 Jun 1994
British Journal of Cancer

Volume: 69, P: 1038-1042
Homozygosity and linkage disequilibrium mapping of autosomal recessive distal myopathy (Nonaka distal myopathy)

T. Asaka
K. Ikeuchi
M. Takamori
Research01 Nov 2001
Journal of Human Genetics

Volume: 46, P: 649-655
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission

Little information is available on molecular changes in response to treatment of rheumatoid arthritis (RA). Here the authors report a multi-omics study collecting patients' transcriptome, proteome, and immunophenotype data to help understand the impact of drug treatments on RA molecular phenotypes.

Shinya Tasaki
Katsuya Suzuki
Tsutomu Takeuchi
ResearchOpen Access16 Jul 2018
Nature Communications

Volume: 9, P: 1-12
Cloning and characterization of the human UDP-N-acetylglucosamine: α-1,3-D-mannoside β-1,4-N-acetylglucosaminyltransferase IV-homologue (hGnT-IV-H) gene

T. Furukawa
E. M. Youssef
A. Horii
Research01 Oct 1999
Journal of Human Genetics

Volume: 44, P: 397-401
Usefulness of bone metabolic markers in the diagnosis and follow-up of bone metastasis from lung cancer

A Aruga
M Koizumi
E Ogata
Research01 Sept 1997
British Journal of Cancer

Volume: 76, P: 760-764
164 BIOCHEMICAL GENETIC ANALYSIS OF NUCLEOSIDE TRANSPORT IN LEISHMANIA DONOVANI PROMASTIGOTES

Buddy Ullman
Research01 Jul 1988
Pediatric Research

Volume: 24, P: 138
Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP)

ABP profiling identifies uncharacterized S. aureus serine hydrolases, including the surface-localized FphB, which processes lipid ester substrates and is required for infection in vivo. An FphB inhibitor reduces in vivo bacterial load.

Christian S. Lentz
Jessica R. Sheldon
Matthew Bogyo
Research16 May 2018
Nature Chemical Biology

Volume: 14, P: 609-617
Tenascin-C Modulates Adhesion of Cardiomyocytes to Extracellular Matrix during Tissue Remodeling after Myocardial Infarction

Kyoko Imanaka-Yoshida
Michiaki Hiroe
Toshimichi Yoshida
Research01 Jul 2001
Laboratory Investigation

Volume: 81, P: 1015-1024
165 GENETIC ANALYSIS OF 2′,3′-DIDEOXYCYTIDINE METABOLISM IN HUMAN CEM T LYMPHOBLASTS

Buddy Ullman
Research01 Jul 1988
Pediatric Research

Volume: 24, P: 138
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation

There is an urgent need for novel strategies to combat life-threatening fungal infections. Here, Revie et al. identify a compound that induces alterations in fungal membranes, synergizes with azole antifungals against the pathogen Candida albicans, and inhibits virulence traits and biofilm formation in animal models of infection.

Nicole M. Revie
Kali R. Iyer
Leah E. Cowen
ResearchOpen Access25 Jun 2022
Nature Communications

Volume: 13, P: 1-20
Risk factors and prognostic factors of hip and knee osteoarthritis

Research into the epidemiology of and risk factors for osteoarthritis has been inconclusive. This Review focuses on data from systematic reviews on risk, incidence and prognostic factors of knee and hip osteoarthritis, and provides insight into how these findings can be interpreted in clinical practice.

Sita MA Bierma-Zeinstra
Bart W Koes
Reviews01 Feb 2007
Nature Clinical Practice Rheumatology

Volume: 3, P: 78-85

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