Abundant evidence suggests a physiological role of magnesium in cardiovascular function. As the kidney is a major regulator of magnesium homeostasis, serum magnesium levels and magnesium balance are often altered in patients with chronic kidney disease (CKD). In this article, Ziad Massy and Tilman Drüeke review the findings of experimental and clinical studies that provide evidence for a role of magnesium in the high frequency of cardiovascular disease in patients with CKD.
- Ziad A. Massy
- Tilman B. Drüeke
