The pathogenesis and treatment of prostate cancer is complex and challenging, and the development of useful biomarkers for disease progression would be extremely valuable to clinicians and patients making treatment decisions. In this Review, the authors suggest a series of algorithms, making up a clinical 'roadmap' of prostate cancer pathogenesis and management. This device could help in identifying points in the prostate cancer timeline where biomarkers are most needed.
- Sheng Fei Oon
- Stephen R. Pennington
- R. William G. Watson
