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Showing 1–10 of 10 results
Advanced filters: Author: Saad Jbabdi Clear advanced filters
  • Brain regions exhibit specialization for different functions, but such functions are constrained by anatomical connections to other brain regions. A study now finds that, by measuring these connections, we can predict complex functional responses before the subject has even performed the task.

    • Saad Jbabdi
    • Timothy E J Behrens
    News & Views
    Nature Neuroscience
    Volume: 15, P: 171-172
  • Linking microscale cellular structures to macroscale features of the brain is required to fully understand its structure and function. Here, the authors present a resource which combines multi-contrast microscopy and MRI of a single whole macaque brain to facilitate multimodal analyses.

    • Amy F. D. Howard
    • Istvan N. Huszar
    • Karla L. Miller
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18
  • Here the authors introduced a multimodal comparative framework to study the primate hippocampus. Despite expected structural conservation, they also observed functional reconfiguration, reflecting evolutionary changes to brain network integration.

    • Nicole Eichert
    • Jordan DeKraker
    • Boris C. Bernhardt
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14
  • After infection with SARS-CoV-2, individuals show a greater reduction in grey matter thickness and tissue contrast in the orbitofrontal cortex and parahippocampal gyrus; greater changes in markers of tissue damage in regions that are functionally connected to the primary olfactory cortex; and a greater reduction in global brain size.

    • Gwenaëlle Douaud
    • Soojin Lee
    • Stephen M. Smith
    ResearchOpen Access
    Nature
    Volume: 604, P: 697-707
  • The neurophysiological basis of neonatal responses to noxious stimulation is poorly understood. Using MRI, the authors observe that neonates’ noxious-stimulus evoked brain activity is coupled to both their resting-state network activity and white matter microstructure.

    • Luke Baxter
    • Fiona Moultrie
    • Rebeccah Slater
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14
  • At macroscopic scales, the human connectome comprises anatomically distinct brain areas, the structural pathways connecting them and their functional interactions. Annotation of phenotypic associations with variation in the connectome and cataloging of neurophenotypes promise to transform our understanding of the human brain. In this Review, we provide a survey of magnetic resonance imaging–based measurements of functional and structural connectivity. We highlight emerging areas of development and inquiry and emphasize the importance of integrating structural and functional perspectives on brain architecture.

    • R Cameron Craddock
    • Saad Jbabdi
    • Michael P Milham
    Reviews
    Nature Methods
    Volume: 10, P: 524-539
  • The UK Biobank combines detailed phenotyping and genotyping with tracking of long-term health outcomes in a large cohort. This study describes the recently launched brain-imaging component that will ultimately scan 100,000 individuals. Results from the first 5,000 subjects are reported, including thousands of associations, population modes and hypothesis-driven results.

    • Karla L Miller
    • Fidel Alfaro-Almagro
    • Stephen M Smith
    Research
    Nature Neuroscience
    Volume: 19, P: 1523-1536
  • Measuring brain connections in humans continues to pose challenges despite the recent advances in MRI technology. The authors contrast methods used in humans with those used in animals and show the extent to which human techniques can inform us about connections despite their limitations.

    • Saad Jbabdi
    • Stamatios N Sotiropoulos
    • Timothy E Behrens
    Reviews
    Nature Neuroscience
    Volume: 18, P: 1546-1555
  • In this Primer article, Bijsterbosch and colleagues provide an accessible discussion of the challenges faced in analytical representations of functional brain organization and provide clear recommendations to unite a fractionated field.

    • Janine Bijsterbosch
    • Samuel J. Harrison
    • Eugene P. Duff
    Reviews
    Nature Neuroscience
    Volume: 23, P: 1484-1495