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Showing 1–3 of 3 results
Advanced filters: Author: Saba R. Aliyari Clear advanced filters

  • Here, Brasil et al. investigate mother to child Zika virus (ZIKV) transmission rates in a large longitudinal cohort of pregnant ZIKV-positive women with their infants followed from the time of maternal infection through birth and onwards, finding high in utero transmission rates that do not predict clinical outcomes, suggesting follow-up of children with antenatal ZIKV exposure is necessary.

    • Patrícia Brasil
    • Zilton Vasconcelos
    • Karin Nielsen-Saines
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8

  • The innate immunity system detects viral pathogens by sensing viral DNA or RNA via distinct pathways, but whether these pathways cross-regulate is unclear. Here the authors show that TRAF3, a known regulator of the RNA-sensing pathway, modulates an NF-κB activator NIK to control DNA-sensing by the adaptor STING in immune cells.

    • Kislay Parvatiyar
    • Jose Pindado
    • Genhong Cheng
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13