Plasmodium sporozoites must invade mosquito salivary glands to facilitate malaria transmission, yet the effects of this invasion are not well understood. Here, the authors use high-resolution proteomics and show that malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission.
- Thiago Luiz Alves e Silva
- Sachi Kanatani
- Joel Vega-Rodriguez
