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Scientific Reports (2)
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Showing 1–3 of 3 results

Advanced filters: Author: Sabrina Guichard Clear advanced filters

Identification of a binding site for small molecule inhibitors targeting human TRPM4

TRPM4 is an ion channel associated with various genetic and cardiovascular disorders. The authors utilized cryo-EM and patch clamp experiments to determine the binding sites of potent and specific TRPM4 inhibitors driving further drug development targeting TRPM4.

Babatunde Ekundayo
Prakash Arullampalam
Dongchun Ni
ResearchOpen Access19 Jan 2025
Nature Communications

Volume: 16, P: 1-14
Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter

Ludovic Gillet
Sabrina Guichard
Hugues Abriel
ResearchOpen Access19 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation

Malorie Blancard
Amal Debbiche
Jean-Sébastien Rougier
ResearchOpen Access02 Oct 2018
Scientific Reports

Volume: 8, P: 1-13