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Advanced filters: Author: Sabrina Kueckelmann Clear advanced filters
  • Degradation of nonsense mediated mRNA decay (NMD) substrates is carried out by two seemingly independent pathways, SMG6-mediated endonucleolytic cleavage and/or SMG5-SMG7-induced accelerated deadenylation. Here the authors show that SMG5-SMG7 maintain NMD activity by permitting SMG6 activation.

    • Volker Boehm
    • Sabrina Kueckelmann
    • Niels H. Gehring
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19