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Advanced filters: Author: Sabrina Schlienger Clear advanced filters
  • The precise regulatory mechanisms controlling ciliary Hedgehog signaling remain incomplete. Here, the authors use ciliary proteomics to reveal that Numb facilitates the endocytosis of the receptor Ptch1 from the ciliary pocket, thereby enabling activation of Hedgehog signaling.

    • Xiaoliang Liu
    • Patricia T. Yam
    • Xuecai Ge
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20