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Showing 1–4 of 4 results
Advanced filters: Author: Saher A. Shaikh Clear advanced filters

  • Survey data collected across ten low-income and middle-income countries (LMICs) in Asia, Africa and South America compared with surveys from Russia and the United States reveal heterogeneity in vaccine confidence in LMICs, with healthcare providers being trusted sources of information, as well as greater levels of vaccine acceptance in these countries than in Russia and the United States.

    • Julio S. Solís Arce
    • Shana S. Warren
    • Saad B. Omer
    ResearchOpen Access
    Nature Medicine
    Volume: 27, P: 1385-1394

  • AMPA receptors associated with TARP subunits enable the development of selective AMPA receptor drugs. Here, the authors provide cryo-EM structures of receptors bound to three TARP-γ8 selective drugs, and reveal bifunctionality of one ligand.

    • Danyang Zhang
    • Remigijus Lape
    • Ingo H. Greger
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • AMPA glutamate receptors, mediate the majority of excitatory signaling in the brain. Here the authors show how the auxiliary subunit TARP-γ8 shapes gating kinetics, ion conductance and rectification properties of the heteromeric GluA1/2 AMPA receptor.

    • Beatriz Herguedas
    • Bianka K. Kohegyi
    • Ingo H. Greger
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Development of a generalized method for dual site-specific incorporation of nonnatural photocaged and photoreactive amino acids into proteins expressed in live cells enabled engineering of a photoreactive photoactive antibody fragment.

    • Thomas Bridge
    • Udo Wegmann
    • Amit Sachdeva
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 19, P: 740-749