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Showing 1–2 of 2 results
Advanced filters: Author: Saixian Zhang Clear advanced filters

  • The mechanism and disease-relevance of pancreatic b-cell heterogeneity remains elusive. Here the authors show that variable HNF1A-FXYD2 activity drives single b-cell heterogeneity at transcriptomic, epigenomic, and electro-physiological levels, which strongly mark the progression of type 2 diabetes.

    • Chen Weng
    • Anniya Gu
    • Yan Li
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • To date, little is known about the regulatory landscape of the pig genome. Here, the authors characterize cis-regulatory elements in the pig genome using RNA-seq, ChIP-Seq and ATAC-seq, finding a higher degree of usage conservation between pig and human than mouse and human.

    • Yunxia Zhao
    • Ye Hou
    • Shuhong Zhao
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17