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Showing 1–5 of 5 results
Advanced filters: Author: Sakshi Garg Clear advanced filters

  • Metabokiller is a novel, explainable AI-backed method for carcinogenicity prediction that leverages the biological and chemical properties associated with carcinogens.

    • Aayushi Mittal
    • Sanjay Kumar Mohanty
    • Gaurav Ahuja
    Research
    Nature Chemical Biology
    Volume: 18, P: 1204-1213

  • The CPJUMP1 Resource comprises Cell Painting images and profiles of 75 million cells treated with hundreds of chemical and genetic perturbations. The dataset enables exploration of their relationships and lays the foundation for the development of advanced methods to match perturbations.

    • Srinivas Niranj Chandrasekaran
    • Beth A. Cimini
    • Anne E. Carpenter
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 1114-1121

  • Two assays reveal the birthplace of target proteins. In both, an antibody against a protein is used alongside an antibody that marks recent translation. The close proximity of both antibodies indicates the newly synthesized target protein.

    • Susanne tom Dieck
    • Lisa Kochen
    • Erin M Schuman
    Research
    Nature Methods
    Volume: 12, P: 411-414

  • We provide an updated protocol for image-based profiling with Cell Painting. A detailed procedure, with standardized conditions for the assay, is presented, along with a comprehensive description of parameters to be considered when optimizing the assay.

    • Beth A. Cimini
    • Srinivas Niranj Chandrasekaran
    • Anne E. Carpenter
    Protocols
    Nature Protocols
    Volume: 18, P: 1981-2013