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Oncogenesis (1)
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Advanced filters: Author: Salsabiel El Nagar Clear advanced filters

Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy

Decreased brain coenzyme Q₁₀ levels cause encephalopathy and are associated with neurodegeneration; supplementation with 4-HMA or 4-HB restores coenzyme Q₁₀ synthesis in mice and humans with HPDL variants, improving survival and neurological symptoms in HPDL-driven mitochondrial encephalopathy.

Guangbin Shi
Claire Miller
Michael E. Pacold
ResearchOpen Access09 Jul 2025
Nature

Volume: 645, P: 466-474
Otx2 promotes granule cell precursor proliferation and Shh-dependent medulloblastoma maintenance in vivo

Salsabiel El Nagar
Almahdi Chakroun
Nathalie Billon
ResearchOpen Access13 Aug 2018
Oncogenesis

Volume: 7, P: 1-12

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Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy

Otx2 promotes granule cell precursor proliferation and Shh-dependent medulloblastoma maintenance in vivo

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