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Showing 1–2 of 2 results
Advanced filters: Author: Salvatore Adinolfi Clear advanced filters

  • Frataxin is an essential protein that has been linked to iron–sulphur cluster assembly, and reduced levels are associated with Friedrich's ataxia. In this study, a combination of techniques is used to probe the interactions of the bacterial frataxin orthologue CyaY with the iron–sulphur cluster assembly machinery.

    • Filippo Prischi
    • Petr V. Konarev
    • Annalisa Pastore
    ResearchOpen Access
    Nature Communications
    Volume: 1, P: 1-10

  • Frataxin is a conserved protein involved in the cellular assembly of iron-sulfur clusters, but its exact role is not clear. Now work on bacterial frataxin CyaY indicates that it acts as an iron-dependent regulator of iron-sulfur cluster formation by the desulfurase IscS.

    • Salvatore Adinolfi
    • Clara Iannuzzi
    • Annalisa Pastore
    Research
    Nature Structural & Molecular Biology
    Volume: 16, P: 390-396