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Showing 1–3 of 3 results
Advanced filters: Author: Salwan Maqdasy Clear advanced filters

  • Lecoutre, Maqdasy and Rizo-Roca show that whole-body pharmacological inhibition or adipocyte-specific deletion of glutaminase in mice activates thermogenesis in inguinal adipocytes and promotes metabolic health. They also link decreased plasma and adipose tissue glutamine-to-glutamate ratios to insulin resistance in humans with obesity.

    • Simon Lecoutre
    • Salwan Maqdasy
    • Mikael Rydén
    ResearchOpen Access
    Nature Metabolism
    Volume: 6, P: 1329-1346

  • Maqdasy, Lecoutre et al. show that increased an phosphocreatine/creatine ratio in white adipocytes drives changes in AMP-activated protein kinase activity and promotes white adipocyte inflammation during obesity.

    • Salwan Maqdasy
    • Simon Lecoutre
    • Mikael Rydén
    ResearchOpen Access
    Nature Metabolism
    Volume: 4, P: 190-202

  • Adipose tissue progenitor cells regulate adipose remodelling and local and systemic metabolism in response to factors such as calorie intake and hormone signalling. Here, the authors discuss the current understanding of adipose progenitor subtypes, the plasticity of these cell types and their roles in metabolic health and disease.

    • Simon Lecoutre
    • Clémentine Rebière
    • Geneviève Marcelin
    Reviews
    Nature Reviews Endocrinology
    Volume: 21, P: 272-288