Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Samarchith P. Kurup Clear advanced filters

  • Pathogen-associated molecular patterns are involved in the initiation of anti-pathogen immunity but their importance for sustaining this response is not established. Here, the authors show that persistent presence of pathogen-associated molecular patterns is required to maintain robust immune responses to pathogens.

    • Samarchith P. Kurup
    • Rick L. Tarleton
    Research
    Nature Communications
    Volume: 4, P: 1-10

  • John Harty and colleagues report that, in mouse models of malaria, regulatory T cells expand, as in humans, and inhibit conventional T cells and germinal center B cells, thereby impairing protective responses against blood-stage disease. Timed blockade of the inhibitory receptor CTLA-4 cured infection in mice and promoted cross-protective blood-stage immunity against a different Plasmodium species.

    • Samarchith P Kurup
    • Nyamekye Obeng-Adjei
    • John T Harty
    Research
    Nature Medicine
    Volume: 23, P: 1220-1225

  • John Harty and colleagues explain how different subsets of CD4+ T cells, CD8+ T cells and γδ T cells respond to the Plasmodium parasites that cause malaria. They discuss the major challenges that need to be overcome in order to harness T cell responses for malaria vaccines and therapies.

    • Samarchith P. Kurup
    • Noah S. Butler
    • John T. Harty
    Reviews
    Nature Reviews Immunology
    Volume: 19, P: 457-471